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Key Documents

183725

Sigma-Aldrich

4-(Imidazol-1-yl)phenol

97%

Synonym(s):

1-(4-Hydroxyphenyl)imidazole

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About This Item

Empirical Formula (Hill Notation):
C9H8N2O
CAS Number:
Molecular Weight:
160.17
EC Number:
MDL number:
UNSPSC Code:
12352005
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

97%

form

powder

mp

204-206 °C (lit.)

SMILES string

Oc1ccc(cc1)-n2ccnc2

InChI

1S/C9H8N2O/c12-9-3-1-8(2-4-9)11-6-5-10-7-11/h1-7,12H

InChI key

CYKCUAPYWQDIKR-UHFFFAOYSA-N

Application

4-(Imidazol-1-yl)phenol was used in evaluation of estrogenicity of phenolic xenoestrogens by Saccharomyces cerevisiae-based Lac-Z reporter assay.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Wan Qiu Xia et al.
Analytical biochemistry, 554, 9-15 (2018-05-29)
In this study, a molecularly imprinted polymer based chemiluminescence array capable of simultaneous determining phenothiazines and benzodiazepines was first reported. Two polymers were coated in different wells of the conventional 96-well microtiter plate as the recognition reagents, and the added
Marimuthu Senthilkumaran et al.
Journal of fluorescence, 27(6), 2159-2168 (2017-09-10)
The interaction of n-(4-hydroxyphenyl)-imidazole with p-sulfonatocalix[4]arene is studied using fluorescence technique. The quenching of fluorescence intensity explains the efficiency of binding via binding constant and quenching constant. The excited state lifetime of n-(4-hydroxyphenyl)-imidazole is decreased upon interaction with p-sulfonatocalix[4]arene. The
Effect of substituent size and dimensionality on potency of phenolic xenoestrogens evaluated with a recombinant yeast assay.
Schultz TW, et al.
Environmental Toxicology and Chemistry / Setac, 19(11), 2637-2642 (2000)
Yi Cai et al.
Food chemistry, 280, 103-109 (2019-01-16)
In this study, a molecularly imprinted polymer capable of recognizing 8 benzimidazoles was first synthesized. The computation simulation showed that the shape and size of used template were the main factors influencing its recognition ability. Then the polymer was used

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