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Merck

V900456

Sigma-Aldrich

L -还原型谷胱甘肽

≥98%, Vetec

别名:

γ-L-谷酰基-L-半胱氨酰-甘氨酸, GSH

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About This Item

线性分子式:
H2NCH(CO2H)CH2CH2CONHCH(CH2SH)CONHCH2CO2H
CAS号:
分子量:
307.32
Beilstein:
1729812
EC號碼:
MDL號碼:
分類程式碼代碼:
12352209
PubChem物質ID:

product name

L -还原型谷胱甘肽, Vetec, reagent grade, ≥98%

等級

reagent grade

產品線

Vetec

化驗

≥98%

形狀

powder

技術

cell culture | mammalian: suitable

顏色

white

mp

192-195 °C (dec.) (lit.)

儲存溫度

2-8°C

SMILES 字串

N[C@@H](CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O)C(O)=O

InChI

1S/C10H17N3O6S/c11-5(10(18)19)1-2-7(14)13-6(4-20)9(17)12-3-8(15)16/h5-6,20H,1-4,11H2,(H,12,17)(H,13,14)(H,15,16)(H,18,19)/t5-,6-/m0/s1

InChI 密鑰

RWSXRVCMGQZWBV-WDSKDSINSA-N

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Amino Acid Sequence

γ-Glu-Cys-Gly

應用

可在5-10 mM下用于从谷胱甘肽琼脂糖洗脱谷胱甘肽S-转移酶(GST)。

生化/生理作用

作为内源性抗氧化剂在减少细胞代谢和呼吸爆发期间生成的活性氧方面发挥重要作用。 谷胱苷肽S-转移酶催化异生素、白三烯和其他亲电子分子生成谷胱苷肽硫醚。 谷胱苷肽也和蛋白质半胱氨酸残基形成二硫键。 经由这些机制,它会产生降低抗癌药功效的逆反效应(paradoxical effect)。

法律資訊

Vetec is a trademark of Merck KGaA, Darmstadt, Germany

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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