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Merck

1478505

USP

奥美拉唑

United States Pharmacopeia (USP) Reference Standard

别名:

5-甲氧基-2 - [[(4-甲氧基-3,5-二甲基-2-吡啶基)甲基]亚磺酰基] -1H-苯并咪唑, Antra, Losec

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About This Item

经验公式(希尔记法):
C17H19N3O3S
CAS号:
分子量:
345.42
MDL號碼:
分類程式碼代碼:
41116107
PubChem物質ID:
NACRES:
NA.24

等級

pharmaceutical primary standard

API 家族

omeprazole

製造商/商標名

USP

應用

pharmaceutical (small molecule)

格式

neat

儲存溫度

2-8°C

SMILES 字串

COc1ccc2[nH]c(nc2c1)S(=O)Cc3ncc(C)c(OC)c3C

InChI

1S/C17H19N3O3S/c1-10-8-18-15(11(2)16(10)23-4)9-24(21)17-19-13-6-5-12(22-3)7-14(13)20-17/h5-8H,9H2,1-4H3,(H,19,20)

InChI 密鑰

SUBDBMMJDZJVOS-UHFFFAOYSA-N

基因資訊

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一般說明

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.Omeprazole is a benzimidazole derivative, which exhibits antisecretory and antiulcer properties. It is a drug with selective and irreversible proton pump inhibition activity, widely used in the treatment of duodenal, gastric ulcers, reflux oesophagitis, and against other acid-related diseases.

應用

Omeprazole USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Esomeprazole Magnesium
  • Esomeprazole Magnesium Delayed-Release Capsules
  • Esomeprazole Strontium
  • Omeprazole
  • Omeprazole Delayed-Release Capsules
  • Omeprazole Magnesium

分析報告

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他說明

Sales restrictions may apply.

相關產品

产品编号
说明
价格

象形圖

Exclamation markEnvironment

訊號詞

Warning

危險聲明

危險分類

Acute Tox. 4 Oral - Aquatic Chronic 2 - Skin Sens. 1

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析证书(COA)

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Analytical method development and validation for the determination of omeprazole and aspirin using reverse phase hplc method in bulk and dosage form
Vani, R and Sunitha, M
Journal of Pharmacological Sciences, 2(4), 25-29 (2017)
Xiaofang Huo et al.
Gut, 63(7), 1042-1052 (2013-09-21)
Oesophagitis might result from the effects of chemokines produced by oesophageal cells in response to gastro-oesophageal reflux, and not solely from the direct, caustic effects of refluxed gastric juice. Proton pump inhibitors (PPI) can block chemokine production through mechanisms independent
J Dent
Alimentary pharmacology & therapeutics, 17 Suppl 1, 5-9 (2003-03-05)
Plasma concentration measurements have confirmed that the advantageous hepatic metabolism of esomeprazole results in a greater delivery of acid suppressant to the systemic circulation, compared with an equal dose of omeprazole. Also, this superior delivery has been shown to cause
R P Myers et al.
The American journal of gastroenterology, 96(12), 3428-3431 (2002-01-05)
Omeprazole is a proton pump inhibitor that is used commonly in the treatment of acid-peptic disorders. Although omeprazole is generally well tolerated, serious adverse effects such as renal failure have been reported. Thus far, 17 cases of acute interstitial nephritis
Anju Nohria et al.
Journal of the American Heart Association, 3(1), e000609-e000609 (2014-01-07)
Inflammation is fundamental to the development of atherosclerosis. We examined the effect of anti-inflammatory doses of salicylate on endothelium-dependent vasodilation, a biomarker of cardiovascular risk, in a broad range of subjects. We performed a randomized, double-blind, placebo-controlled crossover trial evaluating

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