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Key Documents

80023449

TSKgel® UP-SW3000 HPLC Column

phase diol, L × I.D. 15 cm × 4.6 mm, 2 μm particle size

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About This Item

分類程式碼代碼:
41115700

材料

stainless steel

agency

suitable for USP L20
suitable for USP L59

產品線

TSKgel®

製造商/商標名

Tosoh 0023449

參數

≤0.5 M salt concentration
0-30% aqueous soluble organic solvents
0.35 mL/min flow rate
10-30 °C temp. range
340 bar pressure

技術

HPLC: suitable

長度 × 內徑

15 cm × 4.6 mm

基質

silica particle platform

基質活性組

diol phase

粒徑

2 μm

孔徑

250 Å

pH值範圍

2.5-7.5

分離技術

size exclusion (SEC)

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應用

TSKgel® UP-SW3000 HPLC Column may be used for the separation of:
  • Free payloads and related species from antibody drug conjugates (ADCs) and their aggregates, during their determination by using 1-dimensional (1D) gradient size exclusion chromatography (SEC).
  • Protein biopharmaceuticals in aqueous solutions, during their analysis by SEC.

其他說明

Related Catagories: Analytical/Chromatography, HPLC, HPLC & FPLC Columns for Biopolymer Separations, TSKgel Gel Filtration Columns for Proteins and Other Biopolymers, TSKgel Gel Filtration Columns to Analyze Purity and Aggregates, TSKgel Size Exclusion Columns

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法律資訊

TSKgel is a registered trademark of Tosoh Corporation

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分析证书(COA)

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Comprehensive study on the effects of sodium and potassium additives in size exclusion chromatographic separations of protein biopharmaceuticals.
Goyon A, et al.
Journal of Pharmaceutical and Biomedical Analysis, 144, 242-251 (2017)
Extending the limits of size exclusion chromatography: Simultaneous separation of free payloads and related species from antibody drug conjugates and their aggregates.
Goyon A, et al.
Journal of Chromatography A, 1539, 19-29 (2018)

商品

Informative article on size exclusion chromatography columns for biomolecule separations. Using columns packed with sub-2 μm particles provides significant gains in efficiency over SEC columns packed with larger particles.

Informative article on size exclusion chromatography columns for biomolecule separations. Using columns packed with sub-2 μm particles provides significant gains in efficiency over SEC columns packed with larger particles.

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