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Merck

575664-U

Supelco

Supel-Select SCX SPE 96-well Plate

bed wt. 30 mg/well, pk of 1

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About This Item

分類程式碼代碼:
41104018
NACRES:
NB.21

材料

PE frit (20 μm)
polypropylene hardware

品質

MS Friendly

成份

bed wt., 30 mg/well

包裝

pk of 1

技術

solid phase extraction (SPE): suitable

表面積

160-420 m2/g

基質

Sulfonic acid functionalized hydrophilic modified styrene polymer particle platform

基質活性組

sulfonic acid phase

粒徑

50-70 μm

孔徑

80-200 Å pore size

應用

food and beverages

分離技術

ion exchange

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一般說明

Retention Mechanism: Ion-Exchange
Sample Matrix Compatibility: Aqueous solutions (biological fluids, water)

  • Sulfonic acid functionalized hydrophilic modified styrene polymer
  • Developed for the extraction of a highly broad range of compounds from aqueous samples
  • Retention predominately based on ion-exchange; however, because the phase is hydrophilic modified, it is amenable to polar compounds as well.

特點和優勢

  • 价格低廉但具有出色的样品制备性能
  • 可用于通用方法 — 在方法开发时省时、成本低并减少麻烦
  • 容量更大,床重更轻 = 洗脱体积更小 = 处理样品更迅速
  • 能忍受过度干涸,可用于更极端条件的方法
  • 低紫外和质谱可提取物,背景更低,灵敏度更高
  • 严格的生产和质量控制原则提供更好的批次之间、管之间以及孔之间的一致性,能获得更好的准确度和精度

法律資訊

Supel is a trademark of Sigma-Aldrich Co. LLC

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°C)

Not applicable


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商品

Separation of S(+)-Amphetamine (dextro-Amphetamine) solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material; R(-)-Amphetamine (levo-Amphetamine), 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material

Shown here is the chiral separation of amphetamine enantiomers under MS-compatible conditions on Astec CHIROBIOTIC® V2 after extraction from urine using Supel™-Select SCX SPE 96-well plates. The highest grade mobile phase solvents and additives were used to supply low background interference and low particulate contaminants for robust, trouble-free operation. Cerilliant CRMs provided reliable identification and quantification.

SPE retention mechanism in this case is based on the electrostatic attraction of charged functional groups of the analyte(s) to oppositely charged functional groups on the sorbent.

SPE retention mechanism in this case is based on the electrostatic attraction of charged functional groups of the analyte(s) to oppositely charged functional groups on the sorbent.

实验方案

Optimized sample prep and chiral chromatography methods for the LC/MS analysis of these drug enantiomers in urine

In this study, optimized methods are presented for sample preparation and chiral chromatography for the LC/MS analysis of amphetamine and methamphetamine enantiomers in urine.

LC/MS Analysis of Methamphetamine Enantiomers on Astec® CHIROBIOTIC® V2 in Urine after SPE using Supel™-Select SCX

Retention occurs through polar interaction between the sorbent and analytes. Typical sample matrices that can be employed in normal-phase SPE include hydrocarbon or fatty oils diluted in a solvent like hexane, isooctane, chlorinated solvent, THF, diethyl ether, or ethyl acetate.

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