推荐产品
product name
Astec® CHIROBIOTIC® V 手性 HPLC 色谱柱, 5 μm particle size, L × I.D. 25 cm × 4.6 mm
材料
stainless steel column
品質等級
agency
suitable for USP L88
描述
HPLC Column
產品線
Astec®
包裝
pkg of 1 ea
製造商/商標名
Astec®
參數
0-45 °C temperature
241 bar pressure (3500 psi)
技術
HPLC: suitable
LC/MS: suitable
長度 × 內徑
25 cm × 4.6 mm
基質
High-purity silica gel particle platform
fully porous particle
基質活性組
vancomycin phase
粒徑
5 μm
孔徑
100 Å
工作pH值範圍
3.5-7.0
分離技術
chiral
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一般說明
中性分子、酰胺、酸、酯和胺对这些基于万古霉素的CSP具有相当大的对映选择性。在极性离子模式下,在CHIROBIOTIC® V上可分离多种仲胺和叔胺。CHIROBIOTIC® V已被证明具有许多蛋白质固定相的分离特性,但又具有优异的稳定性和更高的样品容量。部分尚无采用其他手性固定相分离报道的手性分析物也已在其上得到分离。CHIROBIOTIC® V和V2的成键化学特性不同,载体颗粒的孔径不同,因而各自具有不同的灵敏度和制备能力。
- 键合相:万古霉素
- 工作pH范围: 3.5 - 7.0
- 粒径:5、10或16 μm
- 孔径:100 Å (CHIROBIOTIC® V)或200 Å (CHIROBIOTIC® V2)
應用
Astec® CHIROBIOTIC® V手性HPLC色谱柱可用于通过填充柱超临界流体色谱法(pSFC)分离不同的外消旋化合物(ß-封闭剂、 ß-激动剂、苯二酚类、非甾体抗炎药、巴比妥酸盐、游离氨基酸和衍生氨基酸。还可用于手性液相色谱法分离人血浆中西酞普兰对映体及其两种N-去甲基代谢物和内标物阿普洛尔。此外,其还可用于手性液相色谱分析酮洛芬和氟比洛芬。
法律資訊
Astec is a registered trademark of Merck KGaA, Darmstadt, Germany
CHIROBIOTIC is a registered trademark of Sigma-Aldrich Co. LLC
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應用
产品编号
说明
价格
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
其他客户在看
Chiral packed column subcritical fluid chromatography on polysaccharide and macrocyclic antibiotic chiral stationary phases.
Journal of Chromatography A, 785 (1), 159-171 (1997)
Biomedical chromatography : BMC, 15(3), 217-222 (2001-06-08)
Vancomycin is an amphoteric, glycopeptide, macrocyclic antibiotic. When attached to 5 microspherical silica gel, vancomycin proved to be an effective chromatographic chiral stationary phase that could be used in the reversed-phase mode. In this study, a bonded vancomycin chiral stationary
Journal of chromatography. B, Biomedical sciences and applications, 719(1-2), 234-238 (1998-12-30)
A procedure using a chirobiotic V column is presented which allows separation of the enantiomers of citalopram and its two N-demethylated metabolites, and of the internal standard, alprenolol, in human plasma. Citalopram, demethylcitalopram and didemethylcitalopram, as well as the internal
Journal of chromatography. A, 1249, 115-129 (2012-07-04)
This paper presents and compares for the first time two chiral LC-QTOF-MS methodologies (utilising CBH and Chirobiotic V columns with cellobiohydrolase and vancomycin as chiral selectors) for the quantification of amphetamine, methamphetamine, MDA (methylenedioxyamphetamine), MDMA (methylenedioxymethamphetamine), propranolol, atenolol, metoprolol, fluoxetine
Analysis of the enantiomers of citalopram and its demethylated metabolites using chiral liquid chromatography
Journal of Chromatography. B, Biomedical Applications, 719 (1-2), 234-238 (1998)
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