推荐产品
化驗
≥99% (TLC)
形狀
powder
溶解度
acetone: 50 mg/mL, clear, colorless to faintly yellow
螢光
λex 333 nm; λem 416 nm in methanol
SMILES 字串
COc1ccc2c(OC(=O)C=C2C(F)(F)F)c1
InChI
1S/C11H7F3O3/c1-16-6-2-3-7-8(11(12,13)14)5-10(15)17-9(7)4-6/h2-5H,1H3
InChI 密鑰
HAZHUELNIGDYQH-UHFFFAOYSA-N
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應用
7-Methoxy-4-(trifluoromethyl)coumarin has been used as a substrate in cytochrome P450 2E1 (CYP2E1) activity assay and aromatase assay.
生化／生理作用
The enzymatic action of cytochrome P450 2E1 (CYP2E1) on 7-methoxy-4-(trifluoromethyl)coumarin results in a fluorescent product 7-hydroxy-4-(trifluoromethyl)coumarin (HFC) that can be measured at 409/530 nm.
訊號詞
Warning
危險聲明
危險分類
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
標靶器官
Respiratory system
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
個人防護裝備
dust mask type N95 (US), Eyeshields, Gloves
Carlo Matera et al.
European journal of pharmacology, 820, 265-273 (2017-12-25)
(±)-3-Methoxy-1-oxa-2,7-diaza-7,10-ethanospiro[4.5]dec-2-ene sesquifumarate (±)-1 was previously characterized as the most selective agonist at α7 neuronal nicotinic acetylcholine receptors in a series of spirocyclic quinuclidinyl-Δ
Gaku Okamatsu et al.
Xenobiotica; the fate of foreign compounds in biological systems, 47(2), 93-102 (2016-03-10)
1. Little is known about drug metabolism in carnivores. Although the domestic cat (Felis catus) is an obligate carnivore and is the most common companion animal, usage and dosage of many drugs are determined according to information obtained from humans and
Vamshi K Manda et al.
Xenobiotica; the fate of foreign compounds in biological systems, 46(2), 117-125 (2015-08-08)
1. Aegle marmelos (bael) is a popular tree in India and other Southeast Asian countries. The fruit is usually consumed as dried, fresh or juice, and is reported to have a high nutritional value and many perceived health benefits. Despite its
Thomas Piper et al.
Drug testing and analysis, 13(5), 916-928 (2020-12-08)
The steroid profile, that is, the urinary concentrations and concentration ratios of selected steroids, is used in sports drug testing to detect the misuse of endogenous steroids such as testosterone. Since several years, not only population-based thresholds are applied but
Yuka Ono et al.
Xenobiotica; the fate of foreign compounds in biological systems, 49(6), 627-635 (2018-06-01)
1. Compared to information for herbivores and omnivores, knowledge on xenobiotic metabolism in carnivores is limited. The cytochrome P450 2C (CYP2C) subfamily is recognized as one of the most important CYP groups in human and dog. We identified and characterized
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