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Merck

T133

Sigma-Aldrich

Inactin® hydrate

≥98% (HPLC)

别名:

Thiobutabarbital sodium salt hydrate

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About This Item

经验公式(希尔记法):
C10H15N2NaO2S · xH2O
CAS号:
分子量:
250.29 (anhydrous basis)
EC號碼:
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:
NACRES:
NA.77

品質等級

化驗

≥98% (HPLC)

形狀

powder

藥物控制

USDEA Schedule IIIN; regulated under CDSA - not available from Sigma-Aldrich Canada

顏色

light yellow

溶解度

H2O: soluble (storage of solutions for more than 8 hours at 4°C is not recommended.)

SMILES 字串

[Na+].CCC(C)C1(CC)C([O-])=NC(=S)NC1=O

InChI

1S/C10H16N2O2S.Na/c1-4-6(3)10(5-2)7(13)11-9(15)12-8(10)14;/h6H,4-5H2,1-3H3,(H2,11,12,13,14,15);/q;+1/p-1

InChI 密鑰

SLZHLQUFNFXTHB-UHFFFAOYSA-M

應用

Inactin® hydrate has been used to anesthetize rats to study stress-induced hypersensitivity and mice to study Cisplatin-induced neuropathy. It has also been used to anesthetize rats to measure the glomerular filtration rate (GFR).

生化/生理作用

Inactin® is a long-lasting rodent anesthetic with minimal effects on cardiovascular tone and renal output. It exhibits sedative and hypnotic properties.

法律資訊

Inactin is a registered trademark of Merck KGaA, Darmstadt, Germany

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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A C Ailiani et al.
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society, 26(10), 1477-1486 (2014-09-27)
Anesthetics are commonly applied in animal studies of gastrointestinal (GI) function. Different anesthetics alter smooth-muscle motility in different ways. The aim of this study is to quantify and compare non-invasively with magnetic resonance imaging (MRI) the motility patterns of the
Maki Niihori et al.
American journal of respiratory cell and molecular biology, 62(2), 231-242 (2019-08-29)
NFU1 is a mitochondrial protein that is involved in the biosynthesis of iron-sulfur clusters, and its genetic modification is associated with disorders of mitochondrial energy metabolism. Patients with autosomal-recessive inheritance of the NFU1 mutation G208C have reduced activity of the
Min-Suk Yoon et al.
BMC neuroscience, 10, 77-77 (2009-07-16)
Cisplatin mediates its antineoplastic activity by formation of distinct DNA intrastrand cross links. The clinical efficacy and desirable dose escalations of cisplatin are restricted by the accumulation of DNA lesions in dorsal root ganglion (DRG) cells leading to sensory polyneuropathy
Flecknell
Laboratory Animal Anesthesia. An introduction for Research Workers and Technicians, 36-36 (1987)
Jing Li et al.
American journal of physiology. Renal physiology, 313(2), F505-F513 (2017-06-02)
We studied gender differences in Na

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