推荐产品
生物源
human
重組細胞
expressed in E. coli
化驗
≥90% (SDS-PAGE)
形狀
liquid
分子量
20 kDa (187 aa, 31-194 aa + His Tag)
包裝
pkg of 100 μg
濃度
1 mg/mL
UniProt登錄號
運輸包裝
dry ice
儲存溫度
−70°C
基因資訊
human ... IL18BP(10068)
一般說明
IL18BP functions as an inhibitor of the proinflammatory cytokine, IL18. It binds IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production, resulting in reduced T-helper type 1 immune responses. This protein is constitutively expressed and secreted in mononuclear cells. Elevated level of this protein is detected in the intestinal tissues of patients with Crohn′s disease. Recombinant human IL18BP protein, fused to His-tag at N-terminus, was expressed in E.coli.
外觀
1 mg/mL in 20 mM Tris-HCl buffer (pH 8.0) containing 0.4 M Urea and 10% glycerol.
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
历史批次信息供参考:
Ahmet Bal et al.
The Journal of surgical research, 201(1), 13-21 (2016-02-07)
The aim of this study was to investigate the possible protective effect of interleukin 18-binding protein (IL-18BP) on ischemia-reperfusion (I/R)-induced liver injury in experimental rat models. Liver is one of the most affected organs from I/R process. IL-18 is an
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