推荐产品
物種活性
human
包裝
kit of 96 wells (12 strips x 8 wells)
技術
ELISA: suitable
輸入
sample type cell culture supernatant(s)
sample type urine
sample type plasma
sample type serum
assay range
inter-assay cv: <10%
intra-assay cv: <12%
sensitivity: 0.5 pg/mL
檢測方法
colorimetric
運輸包裝
wet ice
儲存溫度
−20°C
基因資訊
human ... IL18(3606)
一般說明
该试剂盒中提供的抗体对可检测血清、血浆、细胞培养上清液和尿液中的人 IL-18。白细胞介素-18（IL-18）是一种促炎性细胞因子，在脂肪、肝和骨骼肌等大多数哺乳动物组织中表达。它可作为原 IL-18 产生，其经酶切形成具有信号肽的成熟 IL-18。Il-18 诱导干扰素-γ 介导的 Th1（T 辅助细胞 1）淋巴细胞作用。它控制脂质和葡萄糖的代谢。炎症小体的激活是 IL-18 释放的原因，这是对病毒感染的重要反应。在肾脏和肝脏疾病、糖尿病、动脉粥样硬化、类风湿性关节炎和哮喘等自身免疫性疾病中观察到 IL-18 水平升高。它也与肾功能障碍的发展有关。
應用
人 IL18/白细胞介素-18 ELISA 试剂盒已用于评估巨噬细胞对反式二苯乙烯和三联苯化合物的细胞因子产生。它还已用于分析和测量慢性肾脏病患者尿液中的 IL-18 水平。
仅限研究用途，不可用于诊断。
请参阅随附的一般ELISA试剂盒 操作步骤 （夹心式、竞争性和间接ELISA）
请参阅随附的一般ELISA试剂盒 操作步骤 （夹心式、竞争性和间接ELISA）
其他說明
本产品提供样本分析证书。
请在批号对应的文本框中输入单词 sample 。
请在批号对应的文本框中输入单词 sample 。
试剂盒组分也可单独购买
产品编号
说明
化学品安全说明书
訊號詞
Warning
危險聲明
防範說明
危險分類
Met. Corr. 1
儲存類別代碼
8A - Combustible, corrosive hazardous materials
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Quantification of Inflammasome Adaptor Protein ASC in Biological Samples by Multiple-Reaction Monitoring Mass Spectrometry
Ulke-Lemee A, et al.
Inflammation, 41(4), 1396-1408 (2018)
Annegret Ulke-Lemée et al.
Inflammation, 41(4), 1396-1408 (2018-06-28)
Inflammation is an integral component of many diseases, including chronic kidney disease (CKD). ASC (apoptosis-associated speck-like protein containing CARD, also PYCARD) is the key inflammasome adaptor protein in the innate immune response. Since ASC specks, a macromolecular condensate of ASC
Qi Zeng et al.
Cancer immunology research, 6(5), 566-577 (2018-04-15)
Immunosuppressive myeloid-derived suppressive cells (MDSCs) are characterized by their phenotypic and functional heterogeneity. To better define their T cell-independent functions within the tumor, sorted monocytic CD14+CD11b+HLA-DRlow/- MDSCs (mMDSC) from squamous cell carcinoma patients showed upregulated caspase-1 activity, which was associated
Vaios Vasileios Kaminiotis et al.
Lipids in health and disease, 16(1), 184-184 (2017-09-28)
Atherosclerosis is a chronic inflammatory disease that is promoted, among others, by pro-inflammatory cytokines such as IL-1β and IL-18 produced by NLRP 3 inflammasome. Development of atherosclerotic lesions is also affected by leptin. Furthermore, inflammasome's action is interfered with other
Victor Edgar Fiestas Solórzano et al.
Viruses, 13(9) (2021-09-29)
The incidence of dengue in Latin America has increased dramatically during the last decade. Understanding the pathogenic mechanisms in dengue is crucial for the identification of biomarkers for the triage of patients. We aimed to characterize the profile of cytokines
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系技术服务部门