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Key Documents

SRP3145

Sigma-Aldrich

PLGF-I 人

Animal-component free, recombinant, expressed in E. coli, ≥95% (SDS-PAGE), ≥95% (HPLC), suitable for cell culture

别名:

PGF, PIGF, Placenta Growth Factor-1

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About This Item

分類程式碼代碼:
12352202
NACRES:
NA.32

生物源

human

重組細胞

expressed in E. coli

化驗

≥95% (HPLC)
≥95% (SDS-PAGE)

形狀

lyophilized

分子量

29.7 kDa

包裝

pkg of 25 μg

技術

cell culture | mammalian: suitable

雜質

<0.1 EU/μg endotoxin, tested

顏色

white to off-white

UniProt登錄號

運輸包裝

wet ice

儲存溫度

−20°C

基因資訊

human ... PGF(5228)

一般說明

PLGF-1 is an angiogenic factor that belongs to the cysteine-knot superfamily of growth factors. PLGF-1 is expressed in placental tissues, colon and mammary carcinomas. It signals through the VEGFR-1/FLT1 receptor and stimulates endothelial cell proliferation and migration. Recombinant human PLGF-1 is a 29.7 kDa disulfide-linked homodimeric protein of two 131 amino acid polypeptide chains.

生化/生理作用

PLGF-1 is an angiogenic factor that belongs to the cysteine-knot superfamily of growth factors. Recombinant human PLGF-1 is a 29.7 kDa disulfide-linked homodimeric protein of two 131 amino acid polypeptide chains.

序列

MLPAVPPQQW ALSAGNGSSE VEVVPFQEVW GRSYCRALER LVDVVSEYPS EVEHMFSPSC VSLLRCTGCC GDENLHCVPV ETANVTMQLL KIRSGDRPSY VELTFSQHVR CECRPLREKM KPERCGDAVP RR

外觀

Lyophilized from 10 mM Sodium Phosphate, pH 7.5.

重構

Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a stabilizer (example 5% Trehalose) and store in working aliquots at -20°C to -80°C.

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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J E Park et al.
The Journal of biological chemistry, 269(41), 25646-25654 (1994-10-14)
The recently identified placenta growth factor (PIGF) is a member of the vascular endothelial growth factor (VEGF) family of growth factors. PIGF displays a 53% identity with the platelet-derived growth factor-like region of VEGF. By alternative splicing of RNA, two

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