SML3805

SIRT6-IN-1

≥98% (HPLC)

• 别名: 1,2,3,4-Tetrahydro-2,4-dioxo-N-[4-(3-pyridinyloxy)phenyl]-6-quinazolinesulfonamide, 2,4-Dioxo-N-[4-(3-pyridyloxy)phenyl]-1H-quinazoline-6-sulfonamide, 2,4-dioxo-N-(4-(pyridin-3-yloxy)phenyl)-1,2,3,4-tetrahydroquinazoline-6-sulfonamide
• 经验公式（希尔记法）: C₁₉H₁₄N₄O₅S
• CAS号: 1214468-35-5
• 分子量: 410.40
• MDL號碼: MFCD11667663
• 分類程式碼代碼: 12352200
• NACRES: NA.21

属性

• 品質等級: 100
• 化驗: ≥98% (HPLC)
• 形狀: powder
• 顏色: white to beige
• 溶解度: DMSO: 2 mg/mL, clear (Warmed)
• 儲存溫度: -10 to -25°C

说明

生化／生理作用

SIRT6-IN-1 (2,4-dioxo-N-(4-(pyridin-3-yloxy)phenyl)−1,2,3,4-tetrahydroquinazoline-6-sulfonamide) is a cell penetrant, potent and selective inhibitor of SIRT6 (Sirtuin 6). It improves glucose tolerance in a type 2 diabetes mouse model. SIRT6-IN-1 delays experimental autoimmune encephalomyelitis disease onset in mice.

安全信息

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable