SML3409

ATN-224

≥95% (elemental analysis)

• 别名: 2-hydroxy-N,N,N-trimethylethanaminium tetrathiomolybdate, ALXN1840, Bis-Choline-Tetrathiomolybdate, Tiomolibdate Choline, WTX101
• 经验公式（希尔记法）: C₁₀H₂₈N₂O₂ · MoS₄
• CAS号: 649749-10-0
• 分子量: 432.54
• MDL號碼: MFCD25976790
• 分類程式碼代碼: 12352200
• NACRES: NA.77

属性

• 品質等級: 100
• 化驗: ≥95% (elemental analysis)
• 形狀: powder
• 儲存條件: desiccated
• 顏色: , Orange to very dark red
• 溶解度: H₂O: ≥0.1 mg/mL, clear
• 儲存溫度: -10 to -25°C
• SMILES 字串: S=[Mo]([S-])([S-])=S.C[N+](C)(CCO)C.C[N+](C)(CCO)C
• InChI: 1S/2C5H14NO.Mo.4S/c2*1-6(2,3)4-5-7;;;;;/h2*7H,4-5H2,1-3H3;;;;;/q2*+1;;;;2*-1
• InChI 密鑰: NEYVHGQOGHJAAD-UHFFFAOYSA-N

说明

生化／生理作用

ATN-224 (Bis-Choline-Tetrathiomolybdate) is an orally available and potent inhibitor of superoxide dismutase 1 (SOD1) that exhibit potent anticancer activities. ATN-224 is a copper chelator that rapidly lowers free coper levels and improve clinical symptoms in Wilson′s disease patients.

安全信息

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable