推荐产品
生物源
Nelumbo nucifera
化驗
≥98% (HPLC)
形狀
powder
光學活性
[α]/D -145 to -165°, c = 0.5 in ethanol
顏色
white to beige
溶解度
DMSO: 2 mg/mL, clear (warmed)
儲存溫度
2-8°C
SMILES 字串
[H][C@]1(C2=C3C(OC)=C(OC)C=C2CCN1C)CC4=C3C=CC=C4
InChI
1S/C19H21NO2/c1-20-9-8-13-11-16(21-2)19(22-3)18-14-7-5-4-6-12(14)10-15(20)17(13)18/h4-7,11,15H,8-10H2,1-3H3/t15-/m1/s1
InChI 密鑰
ORJVQPIHKOARKV-OAHLLOKOSA-N
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生化／生理作用
Nuciferine is a major active component from lotus leaf that produces antipsychotic-like effect in rodents. Nuciferine is a potent inverse agonist at human 5-HT7 receptor. Nuciferine attenuates fructose-induced hyperuricemia, dyslipidemia and systemic inflammation in rats.
訊號詞
Danger
危險聲明
危險分類
Acute Tox. 3 Oral
儲存類別代碼
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Ming-Xing Wang et al.
Journal of agricultural and food chemistry (2016-10-11)
Nuciferine is a major active component from lotus leaf. This study examined the effects of nuciferine on fructose-induced renal injury and explored its possible mechanism. Rats consumed drinking water or 10% fructose for 12 wk. Fructose-fed rats were orally treated
Martilias S Farrell et al.
PloS one, 11(3), e0150602-e0150602 (2016-03-11)
The sacred lotus (Nelumbo nucifera) contains many phytochemicals and has a history of human use. To determine which compounds may be responsible for reported psychotropic effects, we used in silico predictions of the identified phytochemicals. Nuciferine, an alkaloid component of
John D Chan et al.
International journal for parasitology. Drugs and drug resistance, 6(3), 364-370 (2016-07-12)
5-hydroxytryptamine (5-HT) is a key regulator of muscle contraction in parasitic flatworms. In Schistosoma mansoni, the myoexcitatory action of 5-HT is effected through activation of a serotonergic GPCR (Sm.5HTR
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