SML1727

EB1089

≥98% (HPLC)

• 别名: (1R,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(1R,2E,4E)-6-Ethyl-6-hydroxy-1-methyl-2,4-octadien-1-yl]octahydro-7a-methyl-4H-inden-4-ylidene]et
• 经验公式（希尔记法）: C₃₀H₄₆O₃
• CAS号: 134404-52-7
• 分子量: 454.68
• MDL號碼: MFCD00871599
• 分類程式碼代碼: 12352200
• PubChem物質ID: 329826042
• NACRES: NA.77

属性

• 品質等級: 100
• 化驗: ≥98% (HPLC)
• 形狀: powder
• 顏色: white to beige
• 溶解度: DMSO: 20 mg/mL, clear
• 儲存溫度: −20°C
• SMILES 字串: C[C@@]12[C@](CC[C@]2([H])[C@@H](/C=C/C=C/C(CC)(O)CC)C)([H])/C(CCC1)=C/C=C3C[C@@H](O)C[C@H](O)C/3=C
• InChI: 1S/C30H46O3/c1-6-30(33,7-2)18-9-8-11-21(3)26-15-16-27-23(12-10-17-29(26,27)5)13-14-24-19-25(31)20-28(32)22(24)4/h8-9,11,13-14,18,21,25-28,31-33H,4,6-7,10,12,15-17,19-20H2,1-3,5H3/b11-8+,18-9+,23-13-,24-14+/t21-,25-,26-,27+,28+,29-/m1/s1
• InChI 密鑰: LVLLALCJVJNGQQ-QMWUBLQMSA-N

说明

生化／生理作用

EB1089 is a Vitamin D analog 50 to 200 times more potent than Vitamin D in inhibiting growth and inducing differentiation with half the hypercalcemic activity. Studies have found EB1089 to be more potent than vitamin D in inhibiting growth and inducing differentiation of some cancer cell lines. EB1089 enhances radio sensitivity of H460 and A549 non-small cell lung cancer (NSCLC) cells.

安全信息

• 危險聲明: H413
• 防範說明: P273 - P501
• 危險分類: Aquatic Chronic 4
• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable