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品質等級
化驗
≥98% (HPLC)
形狀
powder
儲存條件
desiccated
顏色
white to beige
溶解度
H2O: 2 mg/mL, clear (warmed)
運輸包裝
wet ice
儲存溫度
−20°C
一般說明
醋酸依替巴肽是一种环七肽。它属于精氨酸-甘氨酸-天冬氨酸类似物。依替巴肽的半衰期很短。该药物可降低心肌梗死(MI)的风险。醋酸依替巴肽可能与血小板减少症有关。
生化/生理作用
依替巴肽是纤维蛋白原与血小板膜整合素糖蛋白GPIIb/IIIa受体结合的特异性抑制剂。
依替巴肽是纤维蛋白原与血小板膜整合素糖蛋白GPIIb/IIIa受体结合的特异性抑制剂,可预防血小板聚集。依替巴肽进行可逆的竞争性结合。
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
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Rousan TA, et al.
American Journal of Hematology, 85(1), 71-74 (2010)
Current role of platelet glycoprotein IIb/IIIa inhibitors in acute coronary syndromes
Bhatt DL and Topol EJ
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Eptifibatide: A cyclic peptide that selectively inhibits platelet glycoprotein IIb/IIIa
Heras M and Escolar G
Drugs Today (Barc), 36, 295-311 (2000)
Clinical review: traumatic brain injury in patients receiving antiplatelet medication
Beynon C, et al.
Critical Care, 16(4), 228-228 (2012)
Jaqueline Gomes Rosa et al.
Toxicon : official journal of the International Society on Toxinology, 159, 50-60 (2019-01-25)
Victims of Bothrops jararaca snakebites manifest bleedings, blood incoagulability, platelet dysfunction, and thrombocytopenia, and the latter has been directly implicated in the genesis of hemorrhagic diathesis. We addressed herein the direct effects of B. jararaca venom (BjV) on ex vivo
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