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Merck

30165

Sigma-Aldrich

替罗非班

≥98.5% (HPLC)

别名:

N-(丁基磺酰基)-O-[4-(4-哌啶基)丁基]-L-酪氨酸, (2S)-2-(丁基磺酰基氨基)-3-{4-[4-(4-哌啶基)丁氧基}苯基丙酸

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About This Item

经验公式(希尔记法):
C22H36N2O5S
分子量:
440.60
Beilstein:
6182267
MDL號碼:
分類程式碼代碼:
12352106
PubChem物質ID:
NACRES:
NA.25

品質等級

化驗

≥98.5% (HPLC)

形狀

powder

SMILES 字串

CCCCS(=O)(=O)N[C@@H](Cc1ccc(OCCCCC2CCNCC2)cc1)C(O)=O

InChI

1S/C22H36N2O5S/c1-2-3-16-30(27,28)24-21(22(25)26)17-19-7-9-20(10-8-19)29-15-5-4-6-18-11-13-23-14-12-18/h7-10,18,21,23-24H,2-6,11-17H2,1H3,(H,25,26)/t21-/m0/s1

InChI 密鑰

COKMIXFXJJXBQG-NRFANRHFSA-N

基因資訊

應用


  • The efficacy and safety of continuous intravenous tirofiban for acute ischemic stroke patients treated by endovascular therapy: a meta-analysis.:通过meta分析评估急性缺血性卒中患者血管内治疗中连续静脉给药替罗非班的疗效和安全性,具有改善疗效的满意结果(Wang et al., 2024)。

  • Initial Experience with a New Self-Expanding Open-Cell Stent System with Antithrombotic Hydrophilic Polymer Coating (pEGASUS Stent) in the Treatment of Wide-Necked Intracranial Aneurysms.:研究报道首次用新的涂层支架系统治疗颅内动脉瘤(有用到替罗非班),结果疗效和安全性增强(Boxberg et al., 2024)。

包裝

无底玻璃瓶。内含物装在插入的融合锥内。

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Nohra Chalouhi et al.
Neurosurgery, 71(3), 710-714 (2012-06-07)
Thromboembolic complications are a major concern in stent-assisted coiling of intracranial aneurysms that may be prevented with adequate antiplatelet therapy. To assess the safety and efficacy of tirofiban in stent-assisted coiling. Two protocols were used. In the initial protocol, tirofiban
Christoph Kabbasch et al.
Journal of neurointerventional surgery, 11(8), 812-816 (2019-01-25)
Intrasaccular flow disruption represents a new paradigm in endovascular treatment of wide-necked bifurcation aneurysms. To perform a matched case-control study comparing complications and angiographic outcome using the Woven Endobridge (WEB) device and stent-assisted coiling (SAC). Sixty-six patients treated with the
Marco Valgimigli et al.
European heart journal, 31(1), 35-49 (2009-09-17)
To perform a thorough and updated systematic review of randomized clinical trials comparing tirofiban vs. placebo or vs. abciximab. We searched for randomized trials comparing tirofiban vs. placebo or any active control. Odds ratios (OR) were computed from individual studies
Marco Valgimigli et al.
JACC. Cardiovascular interventions, 5(3), 268-277 (2012-03-24)
The authors sought to compare the effect on inhibition of platelet aggregation (IPA) of prasugrel therapy versus tirofiban bolus with or without a post-bolus short drug infusion in ST-segment elevation myocardial infarction (STEMI) patients. The degree and rapidity of IPA
Shukri W David et al.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 93(5), 882-890 (2018-09-29)
In the randomized AMIHOT-II trial, supersaturated oxygen [SSO2 ] delivered into the left anterior descending (LAD) artery via an indwelling intracoronary infusion catheter following primary percutaneous coronary intervention (PCI) significantly reduced infarct size in patients with anterior ST-segment elevation myocardial

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