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品質等級
化驗
≥98% (HPLC)
形狀
powder
顏色
white to beige
溶解度
DMSO: 20 mg/mL, clear
儲存溫度
2-8°C
SMILES 字串
O=S(NC1=C(OC)C=CC(C2=CC=CC=C2)=C1)(C3=C(O)C(Cl)=CC(Cl)=C3)=O
InChI
1S/C19H15Cl2NO4S/c1-26-17-8-7-13(12-5-3-2-4-6-12)9-16(17)22-27(24,25)18-11-14(20)10-15(21)19(18)23/h2-11,22-23H,1H3
InChI 密鑰
SIIPNDKXZOTLEA-UHFFFAOYSA-N
應用
BMS-303141已被用于抑制乳腺癌细胞系中的ATP柠檬酸裂合酶。
生化／生理作用
BMS-303141是ATP柠檬酸裂解酶（ACL）的一种有效抑制剂。
BMS-303141是ATP柠檬酸裂解酶（ACL）的一种有效抑制剂。 BMS-303141可抑制HepG2细胞中的脂质合成，IC50值为8μM。同时，在鼠高脂血症模型中，其可降低血浆中的甘油三酸酯的含量。
危險聲明
防範說明
危險分類
Aquatic Chronic 4
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
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