SML0424

ST247

≥98% (HPLC)

• 别名: 3-[[[4-(Hexylamino)-2-methoxyphenyl]amino]sulfonyl]-2-thiophenecarboxylic acid methyl ester
• 经验公式（希尔记法）: C₁₉H₂₆N₂O₅S₂
• CAS号: 1356497-91-0
• 分子量: 426.55
• 分類程式碼代碼: 12352200
• PubChem物質ID: 329825419
• NACRES: NA.77

属性

• 品質等級: 100
• 化驗: ≥98% (HPLC)
• 形狀: powder
• 顏色: white to beige
• 溶解度: DMSO: 10 mg/mL (clear solution)
• 儲存溫度: 2-8°C
• SMILES 字串: CCCCCCNc1ccc(NS(=O)(=O)c2ccsc2C(=O)OC)c(OC)c1
• InChI: 1S/C19H26N2O5S2/c1-4-5-6-7-11-20-14-8-9-15(16(13-14)25-2)21-28(23,24)17-10-12-27-18(17)19(22)26-3/h8-10,12-13,20-21H,4-7,11H2,1-3H3
• InChI 密鑰: MRWCGEOYGFZZCJ-UHFFFAOYSA-N

说明

生化／生理作用

ST247 is a PPAR β/δ inverse agonist.

ST247 is a PPAR β/δ selective inverse agonist. The compound is based on the structure of GSK0660, and is 10-fold more potent in blocking the transcription of endogenous target genes: ST247 IC₅₀ = 19 nm vs. GSK0660 IC₅₀ = 210 nM.

安全信息

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3