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Merck

SML0117

Sigma-Aldrich

磷苯妥英 二钠盐 水合物

≥98% (HPLC)

别名:

5,5-Diphenyl-3-[(phosphonooxy)methyl]-2,4-imidazolidinedione disodium salt hydrate

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About This Item

经验公式(希尔记法):
C16H13N2Na2O6P · xH2O
CAS号:
分子量:
406.24 (anhydrous basis)
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:
NACRES:
NA.77

化驗

≥98% (HPLC)

形狀

powder

顏色

white to tan

溶解度

H2O: ≥15 mg/mL

儲存溫度

2-8°C

SMILES 字串

O.[Na+].[Na+].[O-]P([O-])(=O)OCN1C(=O)NC(C1=O)(c2ccccc2)c3ccccc3

InChI

1S/C16H15N2O6P.2Na.H2O/c19-14-16(12-7-3-1-4-8-12,13-9-5-2-6-10-13)17-15(20)18(14)11-24-25(21,22)23;;;/h1-10H,11H2,(H,17,20)(H2,21,22,23);;;1H2/q;2*+1;/p-2

InChI 密鑰

WPAVXKKGWCHUAK-UHFFFAOYSA-L

生化/生理作用

Fosphenytoin is a water soluble phenytoin prodrug.

象形圖

Health hazardExclamation mark

訊號詞

Danger

危險聲明

危險分類

Acute Tox. 4 Oral - Carc. 1B - Repr. 1B

儲存類別代碼

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Jun Tanaka et al.
European journal of clinical pharmacology, 69(3), 489-497 (2012-08-25)
We performed a population pharmacokinetic analysis of phenytoin after intravenous administration of fosphenytoin sodium in healthy, neurosurgical, and epileptic subjects, including pediatric patients, and determined the optimal dose and infusion rate for achieving the therapeutic range. We used pooled data
Pue Farooque et al.
Pediatric neurology, 42(3), 215-218 (2010-02-18)
This report describes a 9-year-old child with status epilepticus and cat scratch disease. This patient's focal seizures and electroencephalographic changes persisted for 18 months after status epilepticus. This patient represents the third reported case of persistent focal seizures or electroencephalographic
Video recording devices as a diagnostic aid.
Jeremy Strohkirch et al.
The Journal of emergency medicine, 40(4), e87-e87 (2009-04-07)
Linda A Steinbaugh et al.
Epilepsy & behavior : E&B, 23(3), 280-284 (2012-02-22)
Continuous electroencephalography (cEEG) is increasingly used to detect both clinical and subclinical seizures in patients with traumatic brain injury (TBI) or subarachnoid hemorrhage (SAH). We assess whether EEG findings predict outcomes in TBI/SAH patients enrolled in a levetiracetam (LEV) vs.
Case 3-2009: a 9-month-old boy with seizures.
Ajit Singh Kashyap et al.
The New England journal of medicine, 360(15), 1572-1572 (2009-04-10)

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