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化驗
≥98% (HPLC)
形狀
powder
顏色
white to tan
溶解度
H2O: ≥15 mg/mL
儲存溫度
2-8°C
SMILES 字串
O.[Na+].[Na+].[O-]P([O-])(=O)OCN1C(=O)NC(C1=O)(c2ccccc2)c3ccccc3
InChI
1S/C16H15N2O6P.2Na.H2O/c19-14-16(12-7-3-1-4-8-12,13-9-5-2-6-10-13)17-15(20)18(14)11-24-25(21,22)23;;;/h1-10H,11H2,(H,17,20)(H2,21,22,23);;;1H2/q;2*+1;/p-2
InChI 密鑰
WPAVXKKGWCHUAK-UHFFFAOYSA-L
生化/生理作用
Fosphenytoin is a water soluble phenytoin prodrug.
訊號詞
Danger
危險聲明
危險分類
Acute Tox. 4 Oral - Carc. 1B - Repr. 1B
儲存類別代碼
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
European journal of clinical pharmacology, 69(3), 489-497 (2012-08-25)
We performed a population pharmacokinetic analysis of phenytoin after intravenous administration of fosphenytoin sodium in healthy, neurosurgical, and epileptic subjects, including pediatric patients, and determined the optimal dose and infusion rate for achieving the therapeutic range. We used pooled data
Pediatric neurology, 42(3), 215-218 (2010-02-18)
This report describes a 9-year-old child with status epilepticus and cat scratch disease. This patient's focal seizures and electroencephalographic changes persisted for 18 months after status epilepticus. This patient represents the third reported case of persistent focal seizures or electroencephalographic
Video recording devices as a diagnostic aid.
The Journal of emergency medicine, 40(4), e87-e87 (2009-04-07)
Epilepsy & behavior : E&B, 23(3), 280-284 (2012-02-22)
Continuous electroencephalography (cEEG) is increasingly used to detect both clinical and subclinical seizures in patients with traumatic brain injury (TBI) or subarachnoid hemorrhage (SAH). We assess whether EEG findings predict outcomes in TBI/SAH patients enrolled in a levetiracetam (LEV) vs.
Case 3-2009: a 9-month-old boy with seizures.
The New England journal of medicine, 360(15), 1572-1572 (2009-04-10)
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