所有图片(1)
About This Item
经验公式（希尔记法）:
C12H23N3S
CAS号:
分子量:
241.40
MDL號碼:
分類程式碼代碼:
51111800
PubChem物質ID:
NACRES:
NA.77
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品質等級
化驗
≥98% (HPLC)
形狀
powder
顏色
white to tan
溶解度
DMSO: ≥13 mg/mL
儲存溫度
2-8°C
SMILES 字串
CCCCCCC1CCC\C1=N/NC(N)=S
InChI
1S/C12H23N3S/c1-2-3-4-5-7-10-8-6-9-11(10)14-15-12(13)16/h10H,2-9H2,1H3,(H3,13,15,16)/b14-11+
InChI 密鑰
OWGUSBISUVLUJF-SDNWHVSQSA-N
應用
BLT-1可用于研究在胆固醇流入和流出中起作用的细胞信号通路。
BLT-1（阻断脂质转运-1）已被用作SR-BI（清道夫受体，B类，I型）介导的脂质转移的抑制剂，以确定miR-223-3p是否从多形核中性粒细胞（PMN）输出高密度脂蛋白（HDL）依赖于SR-BI介导的脂质通量。它也被用作SR-BI抑制剂，通过SR-B1研究HDL对单核细胞系中骨钙素（OCN）表达的影响。
生化／生理作用
阻断脂质转运-1（BLT-1）是SR-BI（清道夫受体，B类，I型）介导的脂质转移的特异性抑制剂。该化合物抑制HDL胆固醇醚的细胞选择性脂质摄取和细胞胆固醇向HDL的流出。
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
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