SMB00311

[6]-姜烯酚

≥90% (HPLC)

• 别名: 1-(4-羟基-3-甲氧基苯基)癸-4-烯-3-酮
• 经验公式（希尔记法）: C₁₇H₂₄O₃
• CAS号: 555-66-8
• 分子量: 276.37
• Beilstein: 2056098
• MDL號碼: MFCD01736094
• 分類程式碼代碼: 12352205
• PubChem物質ID: 329824943
• NACRES: NA.25

属性

• 化驗: ≥90% (HPLC)
• 形狀: liquid
• 應用: metabolomics; vitamins, nutraceuticals, and natural products
• 儲存溫度: 2-8°C
• SMILES 字串: CCCCC\C=C\C(=O)CCc1ccc(O)c(OC)c1
• InChI: 1S/C17H24O3/c1-3-4-5-6-7-8-15(18)11-9-14-10-12-16(19)17(13-14)20-2/h7-8,10,12-13,19H,3-6,9,11H2,1-2H3/b8-7+
• InChI 密鑰: OQWKEEOHDMUXEO-BQYQJAHWSA-N

说明

一般說明

Shogaol or 6-shogaol, the pungent metabolite of dried ginger, is one of the main bioactive compounds extracted from the natural dietary rhizome, Zingiber officinale Roscoe (ginger). It is the dehydrated successor of 6-gingerol with an α,β-unsaturated ketone skeleton.

應用

Shogaol has been used to determine its safe dose to evaluate potential toxicity in higher concentrations in mice models. It has also been used to investigate its antioxidant effects on the modulation of TRPC5 (ITRPC5) and TRPA1 (ITRPA1) currents.

生化／生理作用

Shogaols exhibits higher potency, efficacy, and biological activities than gingerols. It is an excellent antioxidant agent, that protects human primary epidermal melanocytes against oxidative stress by activating nuclear factor E2-related factor (Nrf2)-antioxidant response. Shogaol also displays antimicrobial, antifungal, and anti-biofilm activities against Candida albicans, and Candida auris. It exerts anti-inflammatory properties and protects against abdomen irradiation (ABI)-induced intestinal side effects. 6-shogaol also inhibits lipopolysaccharide (LPS)-induced inflammation via peroxisome proliferator-activated receptor gamma (PPAR-γ) activation.

安全信息

• 象形圖: GHS07
• 訊號詞: Warning
• 危險聲明: H302
• 危險分類: Acute Tox. 4 Oral
• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable