推荐产品
生物源
alpaca
重組細胞
expressed in E. coli
共軛
unconjugated (6*his tag and one cys were added at the C terminal of the VHH)
抗體表格
affinity purified immunoglobulin
抗體產品種類
secondary antibodies
無性繁殖
recombinant monoclonal
形狀
lyophilized solid
分子量
14 kDa
物種活性
Alpaca, chicken
技術
ELISA: 1:10000-1:50000
western blot: 1:10000-1:50000
尺寸
0.1 mL
顏色
colorless
同型
VHH
運輸包裝
wet ice
儲存溫度
2-8°C
一般說明
Alpaca Anti-Chicken IgY single domain Antibody is designed to specifically detect chicken IgY. It is a monovalent, single domain, recombinant antibody derived from the variable region of heavy chain of Alpaca pacous. Based on immunoelectrophoresis and/or ELISA, Alpaca Anti-Chicken IgY single domain Antibody detects the chicken IgY selectively but not with mouse, rabbit, human, cynomolgus, rat, goat IgG.
Hens egg yolk immunoglobulins IgY can be transferred from the serum of mother hen to the offspring egg yolk to acquire immunity. In the immunodiagnostic technologies, IgY is an excellent antibody for using in immunological assays involving mammalian sera, due to discriminative properties of IgY compared to mammalian IgG, as IgY does not react with the rheumatoid factor and human anti-mouse IgG antibodies do not activate the complement system and do not bind to Fc receptor. Also, they have poor cross reactivity to mammalian IgG due to immunological differences. IgY does not contain a hinge region but does contain an additional constant domain. The whole IgY molecule possesses both the Fc region and the Fab region, which possessing the epitope-recognition site. The IgYcontains two heavy and light chains. The common IgY is monomeric with a molecular weight of approximately 170 kDa.
VHH are single-domain antibodies derived from the variable regions of heavy chain of Camelidae immunoglobulin. The size of VHH is extremely small(less than15KDa) compared to other forms of antibody fragment, which significantly increase the permeability of VHH. Thus VHH is considered of great value for research, diagnostics and therapeutics.
Hens egg yolk immunoglobulins IgY can be transferred from the serum of mother hen to the offspring egg yolk to acquire immunity. In the immunodiagnostic technologies, IgY is an excellent antibody for using in immunological assays involving mammalian sera, due to discriminative properties of IgY compared to mammalian IgG, as IgY does not react with the rheumatoid factor and human anti-mouse IgG antibodies do not activate the complement system and do not bind to Fc receptor. Also, they have poor cross reactivity to mammalian IgG due to immunological differences. IgY does not contain a hinge region but does contain an additional constant domain. The whole IgY molecule possesses both the Fc region and the Fab region, which possessing the epitope-recognition site. The IgYcontains two heavy and light chains. The common IgY is monomeric with a molecular weight of approximately 170 kDa.
VHH are single-domain antibodies derived from the variable regions of heavy chain of Camelidae immunoglobulin. The size of VHH is extremely small(less than15KDa) compared to other forms of antibody fragment, which significantly increase the permeability of VHH. Thus VHH is considered of great value for research, diagnostics and therapeutics.
特異性
Fc region of chicken IgY
Isotype: VHH domain of alpaca IgG2b/2c
Isotype: VHH domain of alpaca IgG2b/2c
免疫原
Recombinant Alpaca single variable domain secondary nano antibody
包裝
100 μg in Glass bottle
外觀
Lyophilized from 10mM PBS (pH 7.5), 0.05% sucrose, 0.1% trehalose
重構
Add 100uL dH2O or 100uL dH2O with 50% Glycerol to a final concentration of 1mg/mL
儲存和穩定性
After reconstitution, store at –20 °C(Avoid freeze / thaw cycles). Stable for 12 months at -20°C
其他說明
No cross-reactivity with mouse, rabbit, human, cynomolgus, rat, goat IgG
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訊號詞
Warning
危險聲明
危險分類
Aquatic Chronic 3 - Skin Sens. 1
儲存類別代碼
13 - Non Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
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