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Merck
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Key Documents

SAB4502360

Sigma-Aldrich

Anti-PKC δ antibody produced in rabbit

affinity isolated antibody

别名:

KPCD, PKC-δ, PRKCD, kinase PKC-δ, nPKC-δ

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About This Item

MDL號碼:
分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

rabbit

品質等級

共軛

unconjugated

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

buffered aqueous solution

分子量

antigen 77 kDa

物種活性

human, mouse, rat

濃度

~1 mg/mL

技術

ELISA: 1:1000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000

NCBI登錄號

UniProt登錄號

運輸包裝

wet ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... PRKCD(5580)

相关类别

一般說明

Anti-PKC δ antibody detects endogenous levels of total PKC δ protein.
The PKC δ (protein kinase C δ) gene is mapped to human chromosome 3p21.1. It is predominantly expressed in the heart.

免疫原

The antiserum was produced against synthesized peptide derived from human PKC delta.

Immunogen Range: 471-520

生化/生理作用

The PKC (protein kinase C) protein is known to mediate different cellular processes such as transcription regulation, cell signaling, cell proliferation, immune responses and apoptosis. PKC is also associated with learning ability. Abnormal cell signaling induced by PKC is often observed in cancer. PKC δ (protein kinase C δ) regulates neutrophil migration during sepsis. PKC δ has anticancer effect by reducing the cell proliferation rate and also stimulating apoptosis by arresting cell cycle. PKC δ induces neuron proliferation and survival, thereby it is associated with memory.

特點和優勢

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外觀

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

nwg

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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A novel microfluidic assay reveals a key role for protein kinase C ? in regulating human neutrophil-endothelium interaction.
Soroush F
Journal of Leukocyte Biology, 100(5), 1027-1035 (2016)
LAMTOR1-PRKCD and NUMA1-SFMBT1 fusion genes identified by RNA sequencing in aneurysmal benign fibrous histiocytoma with t(3;11)(p21;q13).
Panagopoulos I
Cancer Genetics, 208(11), 545-551 (2015)
MALAT1 in Human Adipose Stem Cells Modulates Survival and Alternative Splicing of PKC?II in HT22 Cells.
El Bassit G
Endocrinology, 158(1), 183-195 (2017)
Polyphenol compounds and PKC signaling.
Das J
Biochimica et Biophysica Acta, 1860(10), 2107-2121 (2016)
Human thrombopoiesis depends on Protein kinase C?/protein kinase C? functional couple.
Carubbi C
Haematologica, 101(7):, 812-820 (2016)

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