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生物源
rabbit
共軛
unconjugated
抗體表格
affinity isolated antibody
抗體產品種類
primary antibodies
無性繁殖
polyclonal
形狀
buffered aqueous solution
分子量
antigen 27 kDa
物種活性
mouse, human, rat
濃度
~1 mg/mL
技術
ELISA: 1:10000
western blot: 1:500-1:1000
NCBI登錄號
UniProt登錄號
運輸包裝
wet ice
儲存溫度
−20°C
目標翻譯後修改
unmodified
基因資訊
human ... PDGFB(5155)
一般說明
Anti-PDGFB Antibody detects endogenous levels of total PDGFB protein.
The platelet derived growth factor receptor β (PDGFRB) gene is mapped to human chromosome 5q32. It encodes for a receptor tyrosine kinase.
免疫原
The antiserum was produced against synthesized peptide derived from human PDGFB.
Immunogen Range: 16-65
Immunogen Range: 16-65
生化/生理作用
Platelet derived growth factor receptor β (PDGFRB) acts as a regulator of mesenchymal cells in tumor cells. Upregulation of the gene is observed in gastric cancer, breast and prostate cancers. Mutations in the gene is associated with infantile myofibromatosis.
特點和優勢
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
外觀
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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儲存類別代碼
10 - Combustible liquids
水污染物質分類(WGK)
nwg
閃點(°F)
Not applicable
閃點(°C)
Not applicable
A genome-wide map of aberrantly expressed chromosomal islands in colorectal cancer.
Molecular Cancer, 5(1), 37-37 (2006)
Quantitative proteomic analysis of gastric cancer tissue reveals novel proteins in platelet-derived growth factor b signaling pathway.
Oncotarget, 8(13), 22059-22075 (2017)
PDGFRB gain-of-function mutations in sporadic infantile myofibromatosis.
Human Molecular Genetics, 26(10), 1801-1810 (2017)
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