跳转至内容
Merck
所有图片(1)

主要文件

SAB2500100

Sigma-Aldrich

Anti-Arginase, Type 1/ARG1 (AB1) antibody produced in goat

affinity isolated antibody, buffered aqueous solution

别名:

Anti-ARG1

登录查看公司和协议定价


About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41
無性繁殖:
polyclonal
application:
ELISA (i)
WB
物種活性:
canine, human
技術:
indirect ELISA: suitable
western blot: suitable
citations:
3

生物源

goat

品質等級

共軛

unconjugated

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

buffered aqueous solution

物種活性

canine, human

技術

indirect ELISA: suitable
western blot: suitable

UniProt登錄號

運輸包裝

dry ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... ARG1(383)

一般說明

Arginase 1 (ARG1) gene with eight exons and seven introns, spanning 10-15kb on genomic DNA, is localized on human chromosome 6q23.2. The protein consists of 322 amino acids and is expressed in the liver, red blood cells, lactating mammalian glands and the kidney.

免疫原

Peptide with sequence C-REGNHKPIDYLNPPK from the C Terminus of the protein sequence according to NP_000036.2.

生化/生理作用

Arginase 1 (ARG1) is a liver enzyme involved in the hydrolysis of arginine to form ornithine and urea. In addition to urea cycle, ARG1 is also implicated in various cellular processes, such as macrophage-mediated cytotoxicity and regulation of immune response. The encoded protein is also involved in allergen challenged lungs, in autoimmune inflammation in the central nervous system and in acute liver injury. Deficiency or mutations in the gene leads to a rare urea cycle disorder, argininemia.

特點和優勢

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外觀

Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

未找到合适的产品?  

试试我们的产品选型工具.

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

没有发现合适的版本?

如果您需要特殊版本,可通过批号或批次号查找具体证书。

已有该产品?

在文件库中查找您最近购买产品的文档。

访问文档库

Clinical phenotype, biochemical profile, and treatment in 19 patients with arginase 1 deficiency
Martina Huemer
Journal of inherited metabolic disease (2016)
Carbon nanotube-based sensing devices for human Arginase-1 detection
S. Baldo
Sensing and Bio-Sensing Research (2016)
Five Novel Mutations in ARG1 Gene in Chinese Patients of Argininemia
Tong-Fei Wu
Pediatric Neurology, 49(2) (2013)

我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门