SAB1300893
Anti-TYRO10 antibody produced in rabbit
saturated ammonium sulfate (SAS) precipitated, buffered aqueous solution
别名:
Anti-Discoidin domain receptor 2, Anti-Neurotrophic tyrosine kinase, Anti-Receptor protein-tyrosine kinase TKT, Anti-Tyrosine-protein kinase TYRO 10, receptor-related 3
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About This Item
推荐产品
生物源
rabbit
品質等級
共軛
unconjugated
抗體表格
saturated ammonium sulfate (SAS) precipitated
抗體產品種類
primary antibodies
無性繁殖
polyclonal
形狀
buffered aqueous solution
物種活性
human
技術
indirect ELISA: 1:1000
western blot: 1:100-1:500
NCBI登錄號
UniProt登錄號
運輸包裝
dry ice
儲存溫度
−20°C
目標翻譯後修改
unmodified
基因資訊
human ... TYRO10(4921)
一般說明
Receptor tyrosine kinases (RTKs) play a key role in the communication of cells with their microenvironment. These molecules are involved in the regulation of cell growth, differentiation and metabolism. In several cases the biochemical mechanism by which RTKs transduce signals across the membrane has been shown to be ligand induced receptor oligomerization and subsequent intracellular phosphorylation. This autophosphorylation leads to phosphorylation of cytosolic targets as well as association with other molecules, which are involved in pleiotropic effects of signal transduction. RTKs have a tripartite structure with extracellular, transmembrane and cytoplasmic regions. There are several subclasses of RTKs and TYRO10 belongs to a novel subclass. The deduced amino acid sequence of TYRO10 has a unique extracellular region encompassing a factor VIII-like domain, not previously described for RTKs.
免疫原
TYRO10 ()
This antibody is generated from rabbits immunized with a his tag recombinant protein of human TYRO10.
This antibody is generated from rabbits immunized with a his tag recombinant protein of human TYRO10.
外觀
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
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儲存類別代碼
10 - Combustible liquids
水污染物質分類(WGK)
nwg
閃點(°F)
Not applicable
閃點(°C)
Not applicable
Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology, 23(6), 335-343 (2014-07-26)
Tissue inhibitor of metalloproteinase-2 (TIMP-2) is an endogenous inhibitor of matrix metalloproteinases (MMPs) that attenuates maladaptive cardiac remodeling in ischemic heart failure. We examined the effects of TIMP-2 on human cardiac fibroblast activation and extracellular matrix (ECM) remodeling. Human cardiac
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