跳转至内容
Merck
所有图片(1)

Key Documents

更多文件

S8326

Sigma-Aldrich

SKI 5C

≥98% (HPLC)

别名:

2,2-Dimethyl-4S-(1-oxo-2-hexadecyn-1-yl)-1,1-dimethylethyl ester-3-oxazolidinecarboxylic acid, SPHK1 Inhibitor 5C

登录查看公司和协议定价
所有图片(1)

About This Item

经验公式（希尔记法）:
C26H45NO4
CAS号:
120005-55-2
分子量:
435.64
MDL號碼:
MFCD18428021
分類程式碼代碼:
12352202
PubChem物質ID:
329824601

品質等級

100

化驗

≥98% (HPLC)

形狀

oil

顏色

colorless to light brown

儲存溫度

2-8°C

SMILES 字串

CCCCCCCCCCCCCC#CC(=O)[C@@H]1COC(C)(C)N1C(=O)OC(C)(C)C

InChI

1S/C26H45NO4/c1-7-8-9-10-11-12-13-14-15-16-17-18-19-20-23(28)22-21-30-26(5,6)27(22)24(29)31-25(2,3)4/h22H,7-18,21H2,1-6H3/t22-/m0/s1

InChI 密鑰

YGBSGZPIDCXNEH-QFIPXVFZSA-N

應用

SKI 5C was used to inhibit Sphingosine kinase 1 in SK-Hep1, HEK-293T cells.1

生化／生理作用

SKI 5C is a selective Sphingosine Kinase 1 (SPHK1) inhibitor.

特點和優勢

This compound is a featured product for Kinase Phosphatase Biology research. Click here to discover more featured Kinase Phosphatase Biology products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ （Lot或Batch）字后找到。

已有该产品？

在文件库中查找您最近购买产品的文档。

访问文档库

Meiyan Bao et al.
Liver international : official journal of the International Association for the Study of the Liver, 32(2), 331-338 (2011-11-22)
Sphingosine kinase 1 (SphK1), which phosphorylates sphingosine to sphingosine-1-phosphate (S1P), is overexpressed in various types of cancers, and may act as an oncogene in tumorigenesis. However, little is known about the precise role of the SphK1/S1P pathway in human liver
Youmna Atieh et al.
Current biology : CB, 31(6), 1129-1140 (2021-01-06)
Extrusion is a mechanism used to eliminate unfit, excess, or dying cells from epithelial tissues. The initial events guiding which cells will be selectively extruded from the epithelium are not well understood. Here, we induced damage in a subset of
Sebastian Wurster et al.
Cell reports, 34(12), 108896-108896 (2021-03-25)
Severe and often fatal opportunistic fungal infections arise frequently following mucosal damage caused by trauma or cytotoxic chemotherapy. Interaction of fungal pathogens with epithelial cells that comprise mucosae is a key early event associated with invasion, and, therefore, enhancing epithelial

我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门