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化驗
≥98% (HPLC)
形狀
powder or solid
顏色
red to brown
溶解度
methanol: 1 mg/mL
應用
metabolomics
vitamins, nutraceuticals, and natural products
儲存溫度
2-8°C
SMILES 字串
C\C(C)=C\CC(O)C1=CC(=O)c2c(O)ccc(O)c2C1=O
InChI
1S/C16H16O5/c1-8(2)3-4-10(17)9-7-13(20)14-11(18)5-6-12(19)15(14)16(9)21/h3,5-7,10,17-19H,4H2,1-2H3
InChI 密鑰
NEZONWMXZKDMKF-UHFFFAOYSA-N
一般說明
紫草素是从紫草根中提取的一种主要的植物化学成分。它是一种天然蒽醌衍生物。
應用
紫草素已被用于：
- 增强吉非替尼对野生型肺癌细胞酪氨酸激酶受体表皮生长因子受体(EGFR)的抗肿瘤活性
- 用作肾脏需氧糖病的抑制剂
- 作为抗炎剂，以测试其改善脂多糖(LPS)诱导的心功能障碍的作用
- 刺激骨髓源性巨噬细胞(BMDM)，检测干扰素调节因子1对细胞死亡的影响
生化／生理作用
从紫草属分离的萘醌。中医（TCM）用于抗炎。抑制趋化因子受体功能并抑制HIV-1。†通过坏死途径诱导细胞死亡，从而避免产生癌症耐药性。† 用紫草素处理癌细胞，通过抑制丙酮酸激酶M2 (PKM2)抑制糖酵解。
紫草素是一种对白色念珠菌生物膜有效的抗真菌剂。它对人胶质瘤细胞具有抗氧化和化疗作用。
訊號詞
Warning
危險聲明
危險分類
Acute Tox. 4 Oral - Aquatic Acute 1
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
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We present an article about how proliferating cells require the biosynthesis of structural components for biomass production and for genomic replication.
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