S1875

(-)-东莨菪碱 氢溴酸盐 三水合物

≥98% (HPLC), powder

• 别名: 天仙子碱 氢溴酸盐, 莨菪胺
• 经验公式（希尔记法）: C₁₇H₂₁NO₄ · HBr · 3H₂O
• CAS号: 6533-68-2
• 分子量: 438.31
• Beilstein: 6100669
• MDL號碼: MFCD00150066
• 分類程式碼代碼: 12352116
• PubChem物質ID: 24277871
• NACRES: NA.77

属性

• 品質等級: 200
• 化驗: ≥98% (HPLC)
• 形狀: powder
• 光學活性: [α]25/D −24 to −26°, c = 5 in H₂O(lit.)
• 顏色: white to off-white
• mp: 195-199 °C (dry matter) (lit.)
• 溶解度: H₂O: 50 mg/mL
• SMILES 字串: O.O.O.Br.CN1[C@@H]2C[C@H](C[C@H]1[C@@H]3O[C@H]23)OC(=O)[C@H](CO)c4ccccc4
• InChI: 1S/C17H21NO4.BrH.3H2O/c1-18-13-7-11(8-14(18)16-15(13)22-16)21-17(20)12(9-19)10-5-3-2-4-6-10;;;;/h2-6,11-16,19H,7-9H2,1H3;1H;3*1H2/t11-,12-,13-,14+,15-,16+;;;;/m1..../s1
• InChI 密鑰: LACQPOBCQQPVIT-SEYKEWMNSA-N
• 基因資訊: human ... CHRM1(1128) , CHRM2(1129) , CHRM3(1131) , CHRM4(1132) , CHRM5(1133)

说明

生化／生理作用

竞争性非选择性毒蕈碱型乙酰胆碱拮抗剂。东莨菪碱所致的实验室动物记忆障碍是常用的记忆缺陷模型。

特點和優勢

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is featured on the Acetylcholine Receptors (Muscarinic) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

安全信息

• 象形圖: GHS06
• 訊號詞: Danger
• 危險聲明: H300 + H310 + H330
• 防範說明: P260 - P262 - P264 - P280 - P302 + P352 + P310 - P304 + P340 + P310
• 危險分類: Acute Tox. 1 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral
• 儲存類別代碼: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable
• 個人防護裝備: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges