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Transfusion, 57(3), 646-656 (2016-12-03)
Riboflavin plus ultraviolet (UV) pathogen reduction technology (RF-PRT) is an effective method for inactivating the residual white blood cells (WBCs) in blood components. The RF-PRT system for platelets is known to activate many signaling pathways, including p38 and NF-κB. Nevertheless
Molecular medicine reports, 16(6), 9613-9619 (2017-10-19)
Patients with intractable epilepsy (IE) exhibit an increased risk of premature death, psychosocial dysfunction and decreasing quality of life. The present study aimed to investigate the alteration in the expression of Rho7 in brain tissue from patients with IE, and
Journal of neuroinflammation, 15(1), 210-210 (2018-07-22)
Alzheimer's disease is characterized by progressive accumulation of β-amyloid (Aβ)-containing amyloid plaques, and microglia play a critical role in internalization and degradation of Aβ. Our previous research confirmed that Nogo-66 binding to Nogo receptors (NgR) expressed on microglia inhibits cell
Oncology reports, 42(5), 1677-1688 (2019-09-24)
MicroRNAs (miRNAs) are involved in the development of various types of cancers. Dysregulation of miR‑205‑5p has been reported in various types of human cancer. However, little is known concerning the role of miR‑205‑5p in renal cell carcinoma (RCC). The pr~esent
Nature immunology, 20(4), 493-502 (2019-03-06)
Interferon-stimulated genes (ISGs) form the backbone of the innate immune system and are important for limiting intra- and intercellular viral replication and spread. We conducted a mass-spectrometry-based survey to understand the fundamental organization of the innate immune system and to
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