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品質等級
物種活性
human
包裝
kit of 96 wells (12 strips x 8 wells)
技術
ELISA: suitable
capture ELISA: suitable
輸入
sample type plasma
sample type cell culture supernatant(s)
sample type serum
sample type urine
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 8 pg/mL
standard curve range: 6.55-1600 pg/mL
檢測方法
colorimetric
運輸包裝
wet ice
儲存溫度
−20°C
基因資訊
human ... IL22(50616)
一般說明
Human Interleukin-22 (IL-22) enzyme-linked immunosorbent assay (ELISA) Kit is an in vitro assay for the quantitative measurement of human IL-22 in biological samples, such as serum, plasma, cell culture supernatants, urine, and/or cell and tissue lysates. IL-22 belongs to the family of IL-10 of cytokines. It is produced by the γδ T cells, CD4+ T helper cells, natural killer T cells, and innate lymphoid cells. It is involved in the activation of signal transducer and activator of transcription 3 and 1 (STAT3/1). IL-22 possesses stage-specific, pro-and anti-tumor effects.
免疫原
Recombinant Human IL-22
應用
请参考Protocol了解详情。
其他說明
A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.
Please type the word sample in the text box provided for lot number.
试剂盒组分也可单独购买
产品编号
说明
化学品安全说明书
訊號詞
Warning
危險聲明
防範說明
危險分類
Met. Corr. 1
儲存類別代碼
8A - Combustible corrosive hazardous materials
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The Th17 cytokines interleukin-17A (IL-17A), IL-17F, and IL-22 are critical for the lung immune response to a variety of bacterial pathogens, including Klebsiella pneumoniae. Th2 cytokine expression in the airways is a characteristic feature of asthma and allergic airway inflammation.
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Hashimoto's thyroiditis (HT) is considered to be a Th1-related autoimmune disease (AID). Recent studies revealed that Th17 lymphocytes (producing mostly IL-17, IL-21 and IL-22) play a major role in numerous AIDs commonly thought to be Th1 diseases. More recently, another
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Mohan S Maddur et al.
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Dendritic cells (DCs) play a critical role in immune homeostasis by regulating the functions of various immune cells, including T and B cells. Notably, DCs also undergo education on reciprocal signalling by these immune cells and environmental factors. Various reports
Bérangère Massot et al.
Journal of immunology (Baltimore, Md. : 1950), 192(12), 5635-5642 (2014-05-09)
Naive CD4 lymphocytes undergo a polarization process in the periphery to become induced Th17 (iTh17) cells. Using retinoic acid-related orphan receptor γt (RORγt)-gfp mice, we found that RORγt and the transcription factor promyelocytic leukemia zinc finger (PLZF) are valuable new
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