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Merck

R4653

Sigma-Aldrich

Anti-hnRNP-A2/B1 antibody, Mouse monoclonal

clone DP3B3, purified from hybridoma cell culture

别名:

Anti-Heterogeneous Nuclear Ribonucleoprotein-A2/B1

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About This Item

MDL號碼:
分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

mouse

品質等級

共軛

unconjugated

抗體表格

purified immunoglobulin

抗體產品種類

primary antibodies

無性繁殖

DP3B3, monoclonal

形狀

buffered aqueous solution

分子量

antigen ~36 kDa

物種活性

rat, human, bovine, hamster, monkey, chicken, mouse, canine

技術

immunocytochemistry: suitable
immunoprecipitation (IP): suitable
microarray: suitable
western blot: 1-2 μg/mL using total cell extract from 293T cell line

同型

IgG2a

UniProt登錄號

運輸包裝

dry ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

一般說明

Monoclonal Anti-hnRNP-A2/B1 (mouse IgG2a isotype) is derived from the DP3B3 hybridoma produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice immunized with recombinant human hnRNP-A2. hnRNP-A2/B1 proteins are located in the nucleus of most tissues cells. However, the hnRNP-A2 protein is found also in the cytoplasm of skin and esophagus cells. In rat brain, hnRNP-A2/B1 proteins are found in neurons in the cerebral cortices, hippocampal formation, olfactory regions, caudate-putamin and the supraoptic nucleus of the hypothalamus.

免疫原

recombinant human hnRNP-A2.

應用

Monoclonal Anti-hnRNP-A2/B1 antibody produced in mouse been used in :
  • enzyme linked immunosorbent assay (ELISA)
  • immunoblotting
  • immunoprecipitation
  • immunocytochemistry

生化/生理作用

In cells, it actively participates in pre-messenger RNA (pre-mRNA) processing, mRNA metabolism and transportation. It is overexpressed in the initial stage of lung cancer and in premalignant lesions. It also participates in neurodegeneration mediated by rCGG (repeats).

外觀

Solution in 0.01 M phosphate buffered saline, pH 7.4, and 15 mM sodium azide.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

nwg

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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