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P6149

Sigma-Aldrich

黄体酮

γ-irradiated, BioXtra, suitable for cell culture

别名:

4-孕烯-3,20-二酮

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About This Item

经验公式（希尔记法）:
C21H30O2
CAS号:
57-83-0
分子量:
314.46
Beilstein:
1915950
EC號碼:
200-350-6
MDL號碼:
MFCD00003658
分類程式碼代碼:
12352209
PubChem物質ID:
24898649
NACRES:
NA.77

生物源

synthetic (organic)

品質等級

200

描述

synthesized from materials derived from plant source

無菌

γ-irradiated

產品線

BioXtra

化驗

≥99%

形狀

powder

效力

0.1-20 ng/mL

技術

cell culture | mammalian: suitable

mp

128-132 °C (lit.)

溶解度

chloroform: 50 mg/mL, clear, colorless to light yellow

運輸包裝

ambient

儲存溫度

room temp

SMILES 字串

CC(=O)[C@H]1CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C

InChI

1S/C21H30O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h12,16-19H,4-11H2,1-3H3/t16-,17+,18-,19-,20-,21+/m0/s1

InChI 密鑰

RJKFOVLPORLFTN-LEKSSAKUSA-N

基因資訊

human ... ABCB1(5243) , AR(367) , CYP2C9(1559) , EBP(10682) , ESR1(2099) , ESR2(2100) , NR3C1(2908) , NR3C2(4306) , PGR(5241) , SERPINA6(866)
mouse ... Esr1(13982)
rat ... Ar(24208) , Nr3c1(24413) , Pgr(25154)

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應用

可用于细胞培养应用中研究固醇对细胞信号传导和基因表达的调节。

生化／生理作用

诱导子宫内皮细胞的成熟和分泌活性；抑制排卵。 孕激素与乳腺癌发病有关。

其他說明

黄体分泌的类固醇激素。

外觀

粉末（室温）；（储备液）按使用分量分成小份冻存，以避免使用时反复冻融

重構

添加1 ml纯酒精，轻轻晃动使其溶解，再添加49 ml无菌培养基，制备获得20 μg/ml储备液。

象形圖

Health hazard
GHS08

訊號詞

Danger

危險聲明

H351,H360FD,H362

危險分類

Carc. 2 - Lact. - Repr. 1A

儲存類別代碼

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges

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