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![聚[d（I-C）] lyophilized, pkg of 10 U (10108812001 [A<sub>260</sub> units]), pkg of 50 U (11219847001 [A<sub>260</sub> units])](/deepweb/assets/sigmaaldrich/product/images/352/091/ef743cea-ccd8-44f1-8f3b-dec5a1e4f5d1/640/ef743cea-ccd8-44f1-8f3b-dec5a1e4f5d1.jpg)
應用
聚（脱氧肌苷 - 脱氧胞苷）酸钠盐已用于p65蛋白和neuro-2A蛋白裂解物的电泳迁移位移试验。它还被用作蛋白精氨酸甲基转移酶1（PRMT1）和DNA甲基转移酶1（DNMT1）选择性测定中的底物。
聚（脱氧肌苷 - 脱氧胞苷）酸钠盐已用于合成和表征双（2-（嘧啶-2-γl）乙氧基）烷烃及其药理活性的研究中。聚（脱氧肌苷 - 脱氧胞苷）酸钠盐也已用于研究碳酸钙薄膜在LB/LbL基质上生长。
聚（脱氧肌苷-脱氧胞苷）酸（聚（dI-dC）•聚（dI-dC））是可用作DNA底物的交替共聚物，其可用于评估DNA甲基转移酶（如DNA甲基转移酶1），以及作为双链DNA模型用于DNA结构动力学和药物、小分子、相互作用的构象研究。
生化／生理作用
聚（2′-脱氧肌苷-2′-脱氧胞苷酸），聚（dI-dC）是一种合成的DNA底物。在高盐下，Poly（dI-dC）以左旋螺旋构象存在，并在降低盐浓度过程中恢复为右旋形式。它可用于电泳迁移位移试验（EMSA）。
其他說明
双链交替共聚物
單位定義
在20mM磷酸钠/100mMNaCl(pH 7.0)缓冲液中，一个单位可在1.0ml中产生A260 = 1.0（1cm光程）
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
其他客户在看
Chao Bi et al.
Plant molecular biology, 95(4-5), 425-439 (2017-09-20)
Nuclear factor Y (NF-Y) family proteins are involved in many developmental processes and responses to environmental cues in plants, but whether and how they regulate phytohormone abscisic acid (ABA) signaling need further studies. In the present study, we showed that
Base-specific and enantioselective studies for the DNA binding of iron(II) mixed-ligand complexes containing 1,10-phenanthroline and dipyrido[3,2-a:2',3'-c]phenazine.
Mudasir, Wijaya K, Wahyuni ET, et al.
Spectrochimica Acta Part A: Molecular Spectroscopy, 66, 163-170 (2007)
Identification of Selective, Cell Active Inhibitors of Protein Arginine Methyltransferase 5 through Structure-Based Virtual Screening and Biological Assays
Ye F, et al.
Journal of Chemical Information and Modeling, 58(5), 1066-1073 (2018)
Dexamethasone treatment of calves latently infected with bovine herpesvirus 1 leads to activation of the bICP0 early promoter, in part by the cellular transcription factor C/EBP-alpha
Workman A, et al.
Journal of Virology, 83(17), 8800-8809 (2009)
Chao Bi et al.
Plant molecular biology, 94(1-2), 197-213 (2017-04-10)
It has been known that ABA INSENSITIVE 5 (ABI5) plays a vital role in regulating seed germination. In the present study, we showed that inhibition of the catalase activity with 3-amino-1,2,4-triazole (3-AT) inhibits seed germination of Col-0, abi5 mutants and
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