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一般說明
前列腺特异性抗原（PSA）是含有237个氨基酸的26kDa单链糖蛋白，由定位于人19号染色体的激肽释放酶基因编码。它由人前列腺组织特异性表达，并且是一种在精液中表达的高度丰富的蛋白水解酶。
生化／生理作用
前列腺特异性抗原（PSA）是由前列腺组织特异性产生的由雄激素调节的丝氨酸蛋白酶，并且分泌至组织腔内。精液中的PSA可裂解精液凝固物中存在的精液凝集素。前列腺癌（PCa）患者的血清中总PSA水平升高。 PSA可作为PCa的潜在生物标志物。 血清蛋白酶抑制剂如α 1-抗胰凝乳蛋白酶（α 1-ACT）、α 2-巨球蛋白（α 2-M）和其他急性期蛋白，可与循环PSA形成不可逆复合物并阻碍PSA的蛋白水解活性。
前列腺特异性抗原（PSA）是腺激肽释放酶家族一种糖蛋白，其是一种具有胰凝乳蛋白酶样酶活性的丝氨酸蛋白酶。循环PSA以游离和蛋白酶抑制剂结合的形式存在。通过研究游离形式与抑制剂结合形式的比例可能有助于前列腺癌的诊断。
外觀
溶于10mM Tris（pH 8.0），0.1％叠氮化钠溶液中
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
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