生物源
rabbit
品質等級
共軛
unconjugated
抗體表格
affinity isolated antibody
抗體產品種類
primary antibodies
無性繁殖
polyclonal
形狀
buffered aqueous glycerol solution
分子量
antigen ~120 kDa
物種活性
Xenopus
技術
western blot: 1:1,000 using Xenopus lysates
運輸包裝
wet ice
儲存溫度
−20°C
基因資訊
Xenopus laevis ... stk10-a(373731)
一般說明
Polo-Like Kinase Kinase (PLKK) is a 120kD protein that belongs to the serine/threonine kinase family. It has a crucial role in regulating cellular events in cytokinesis and mitosis. Anti-phospho-polo-like kinase kinase (pSer482, pSer486, pSer490) antibody can be used in immunoblotting (diluted 1:1000). Rabbit anti- phospho-polo-like kinase kinase antibody reacts specifically with phospho-polo-like kinase kinase of xenopus.
免疫原
synthetic phosphopeptide corresponding to amino acids residues surrounding the Xenopus polo-like kinase kinase phosphorylated on serines 482, 486 and 490.
應用
Anti-phospho-polo-like kinase kinase (pSer482, pSer486, pSer490) antibody can be used in western blotting (diluted 1:1000).
外觀
Solution in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 μg/mL BSA, and 50% glycerol.
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儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
A Kumagai et al.
Science (New York, N.Y.), 273(5280), 1377-1380 (1996-09-06)
Cdc2, the cyclin-dependent kinase that controls mitosis, is negatively regulated by phosphorylation on its threonine-14 and tyrosine-15 residues. Cdc25, the phosphatase that dephosphorylates both of these residues, undergoes activation and phosphorylation by multiple kinases at mitosis. Plx1, a kinase that
Y W Qian et al.
Science (New York, N.Y.), 282(5394), 1701-1704 (1998-11-30)
The Xenopus polo-like kinase 1 (Plx1) is essential during mitosis for the activation of Cdc25C, for spindle assembly, and for cyclin B degradation. Polo-like kinases from various organisms are activated by phosphorylation by an unidentified protein kinase. A protein kinase
Xingjie Ma et al.
Aging cell, 17(6), e12831-e12831 (2018-09-15)
Calcium signaling is emerging as a key pathway controlling cellular senescence, a stable cell proliferation arrest playing a fundamental role in pathophysiological conditions, such as embryonic development, wound healing, cancer, and aging. However, how calcium signaling is regulated is still
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