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品質等級
化驗
≥96% (HPLC)
形狀
powder
藥物控制
regulated under CDSA - not available from Sigma-Aldrich Canada
顏色
white
溶解度
DMSO: ~12 mg/mL
H2O: insoluble
儲存溫度
2-8°C
SMILES 字串
[H]O[H].O[C@@H]1CC[C@@]2(O)[C@H]3Cc4ccc(O)c5O[C@@H]1[C@]2(CCN3CC6CC6)c45
InChI
1S/C20H25NO4.H2O/c22-13-4-3-12-9-15-20(24)6-5-14(23)18-19(20,16(12)17(13)25-18)7-8-21(15)10-11-1-2-11;/h3-4,11,14-15,18,22-24H,1-2,5-10H2;1H2/t14-,15-,18+,19+,20-;/m1./s1
InChI 密鑰
VHGGWFVHXKTOPK-CDHBEYIESA-N
生化／生理作用
Neutral antagonist of the μ-opioid receptor. A reduction of withdrawal effects associated with neutral μ-opioid receptor antagonists may offer advantages in treating opioid overdose and addiction.
特點和優勢
This compound is featured on the Opioid Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
Kirsten M Raehal et al.
The Journal of pharmacology and experimental therapeutics, 313(3), 1150-1162 (2005-02-18)
The mu-opioid receptor displays basal signaling activity, which seems to be enhanced by exposure to opioid agonists. This study assesses the in vivo pharmacology of the putative "neutral" antagonist 6beta-naltrexol in comparison to other ligands with varying efficacy, such as
商品
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