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一般說明
神经氨酸酶是糖苷水解酶,催化末端唾液酸残基的水解。最知名的莫过于促进流感病毒释放的病毒近酰胺酶。
應用
来自霍乱弧菌的神经氨酸苷酶已在一项研究中使用,以评估其在易感细胞结合和摄取霍乱毒素中的作用。它还已在另一项研究中使用,以研究钠底物的制备及其在神经氨酸酶荧光测定中的应用。
神经氨酸酶被用作糖缀合物分布和底物特异性研究的细胞表面探针。
生化/生理作用
霍乱弧菌神经氨酸酶已被证明通过结合霍乱毒素并帮助其被细胞摄取来促进霍乱毒素感染。
品質
不含防腐剂。
單位定義
除非另有说明,否则在37 °条件下,当pH为5.0时,使用NAN-乳糖或牛颌下粘蛋白,一个单位每分钟将释放1.0 μ摩尔的N-乙酰神经氨酸。价格基于将NAN-乳糖用作底物的单位。
外觀
水溶液,pH 5.5,含0.15 M NaCl和4 mM CaCl2。
準備報告
色谱纯化产品。
訊號詞
Danger
危險聲明
危險分類
Resp. Sens. 1
儲存類別代碼
10 - Combustible liquids
水污染物質分類(WGK)
WGK 1
閃點(°F)
Not applicable
閃點(°C)
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
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