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Merck

M8639

Sigma-Aldrich

2'-(4-甲基伞形酮)-α;-(4-甲基伞形酮)-α- D - N -乙酰神经氨酸 钠盐 水合物

fluorogenic, ≥95% (HPLC), powder

别名:

4-甲基伞形酮基- N -乙酰基-α- D -神经氨酸 钠盐 水合物

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About This Item

经验公式(希尔记法):
C21H24NNaO11 · xH2O
CAS号:
分子量:
489.41 (anhydrous basis)
分類程式碼代碼:
12352204
PubChem物質ID:
NACRES:
NA.32

product name

2'-(4-甲基伞形酮)-α;-(4-甲基伞形酮)-α- D - N -乙酰神经氨酸 钠盐 水合物, ≥95% (HPLC)

化驗

≥95% (HPLC)

形狀

powder

溶解度

water: 50 mg/mL, clear to slightly hazy, colorless to light yellow

儲存溫度

−20°C

SMILES 字串

O.[H]C(O)(CO)[C@]([H])(O)[C@@H]1OC(C[C@H](O)[C@H]1NC(C)=O)(Oc2ccc3C(C)=CC(=O)Oc3c2)C(=O)O[Na]

InChI

1S/C21H25NO11.Na.H2O/c1-9-5-16(27)31-15-6-11(3-4-12(9)15)32-21(20(29)30)7-13(25)17(22-10(2)24)19(33-21)18(28)14(26)8-23;;/h3-6,13-14,17-19,23,25-26,28H,7-8H2,1-2H3,(H,22,24)(H,29,30);;1H2/q;+1;/p-1/t13-,14?,17+,18?,19+,21+;;/m0../s1

InChI 密鑰

NSQMRVBWXQQIKF-NVRWCLOTSA-M

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生化/生理作用

神经氨酸酶荧光测定法的底物。用于 PAGE 中唾液酸酶的荧光染色。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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A Y Fedorov et al.
Voprosy virusologii, 65(2), 113-118 (2020-06-10)
The classic hemagglutination inhibition reaction (RTGA) is used to determine the level of antiviral antibodies in human and animal serum specimens. During the performance of RTGA the tested sera must be treated with a receptor-destroying enzyme (RDE) to remove serum
Li Zhang et al.
Viruses, 12(5) (2020-05-24)
Influenza virus infections can lead to viral pneumonia and acute respiratory distress syndrome in severe cases, causing significant morbidity and mortality and posing a great threat to human health. Because of the diversity of influenza virus strains and drug resistance
Amanda R Luu et al.
The Journal of biological chemistry, 295(39), 13556-13569 (2020-07-31)
Mutations in the galactosidase β 1 (GLB1) gene cause lysosomal β-galactosidase (β-Gal) deficiency and clinical onset of the neurodegenerative lysosomal storage disease, GM1 gangliosidosis. β-Gal and neuraminidase 1 (NEU1) form a multienzyme complex in lysosomes along with the molecular chaperone
Guo-Yun Chen et al.
eLife, 3, e04066-e04066 (2014-09-05)
Both pathogen- and tissue damage-associated molecular patterns induce inflammation through toll-like receptors (TLRs), while sialic acid-binding immunoglobulin superfamily lectin receptors (Siglecs) provide negative regulation. Here we report extensive and direct interactions between these pattern recognition receptors. The promiscuous TLR binders
Ge Liu et al.
Virologica Sinica, 34(6), 648-661 (2019-07-10)
Severe influenza infections are often associated with the excessive induction of pro-inflammatory cytokines, which is also referred to as "cytokine storms". Several studies have shown that cytokine storms are directly associated with influenza-induced fatal acute lung injury and acute respiratory

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