推荐产品
product name
4-甲基伞形酮基 N-乙酰基-β- D -氨基葡萄糖, suitable for fluorescence, ≥99.0% (TLC)
品質等級
化驗
≥99.0% (TLC)
形狀
powder
雜質
≤0.1% free 4-methylumbelliferone
溶解度
DMF: 20 mg/mL, clear, colorless
螢光
λex 317 nm (pH 10.0)
λex 365 nm; λem 445 nm in aqueous buffer pH 5.0 (after cleavage by β-N-acetylglucosaminidase)
適合性
suitable for fluorescence
儲存溫度
−20°C
SMILES 字串
[H]O[H].[H]O[H].CC(=O)N[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1Oc2ccc3C(C)=CC(=O)Oc3c2
InChI
1S/C18H21NO8.2H2O/c1-8-5-14(22)26-12-6-10(3-4-11(8)12)25-18-15(19-9(2)21)17(24)16(23)13(7-20)27-18;;/h3-6,13,15-18,20,23-24H,7H2,1-2H3,(H,19,21);2*1H2/t13-,15-,16-,17-,18-;;/m1../s1
InChI 密鑰
PAVCYMSNMRWMAK-DMYIEBNJSA-N
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應用
4-甲基伞形酮N-乙酰-β-D-氨基葡萄糖苷在酸性几丁质酶活性测定中用作荧光底物。它还用于测定水样滤液中β-N-乙酰己糖胺酶(NAGase)的总活性。
生化／生理作用
4-甲基伞形酮-N-乙酰-β-D-氨基葡萄糖苷(4-MUF-NAG)是一种用于氨基己糖苷酶的合成不带电荧光底物。它由几丁质单体（N-乙酰-β-D-氨基葡糖苷）和4-甲基伞形酮（7-氢氧基-4-甲基香豆素）(4-MUF)组成。4-MUF-NAG用于通过测定β-N-乙酰己糖胺酶(NAGase)活性来检测和估计真菌的生长。
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
其他客户在看
R M Clegg et al.
Biochemistry, 22(20), 4797-4804 (1983-09-27)
Temperature-jump relaxation methods have been used to study the binding kinetics of fluorescent 4-methylumbelliferyl glycosides of N-acetyl-beta-D-glucosamine and its beta (1 leads to 4)-linked di- and trisaccharides with wheat germ agglutinin. The mono- and disaccharide derivatives yielded biexponential progress curves.
C Emiliani et al.
The International journal of biochemistry, 23(2), 215-219 (1991-01-01)
1. Rat liver beta-N-acetylhexosaminidase was separated into several different molecular forms by DEAE-cellulose chromatography. 2. The subunit composition of the isoenzymes, as well as the similarities to human hexosaminidases, were determined by using the specific active alpha subunit substrate 4-methylumbelliferyl-beta-N-acetylglucosamine-6-sulphate.
C T Yuen et al.
Annals of clinical biochemistry, 21 ( Pt 4), 295-300 (1984-07-01)
This paper describes a comparison of the recently developed substrate 2-methoxy-4-(2'-nitrovinyl)-phenyl-2-acetamido-2-deoxy-beta-D-gluc opyranoside (MNP-GlcNAc) and the corresponding 4-methylumbelliferyl substrate (4-MU-GlcNAc) for the determination of urinary NAG. A good correlation (r = 0.977) was found between NAG activities in 366 urine samples
Nick Konkol et al.
Journal of microbiological methods, 80(2), 178-182 (2009-12-23)
A wide variety of cultural heritage materials are susceptible to fungal deterioration. The paper, canvas, and stone constituents of our cultural heritage are subjected to harmful physical and chemical processes as they are slowly consumed by fungi. Remediation of fungal
W He et al.
Prenatal diagnosis, 14(1), 17-22 (1994-01-01)
A new fluorogenic substrate, 4-methylumbelliferyl beta-D-glucosaminide, was used for the assay of acetyl CoA:glucosaminide N-acetyltransferase in chorionic villi, cultured villus cells, and amniocytes. Optimal conditions for the assay and the ranges of enzyme activity were established for the various types
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