所有图片(1)
About This Item
经验公式（希尔记法）:
C17H15NO3
CAS号:
分子量:
281.31
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:
NACRES:
NA.77
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品質等級
化驗
≥98% (HPLC)
形狀
solid
顏色
tan
溶解度
DMSO: soluble 3 mg/mL at 60 °C
H2O: insoluble
運輸包裝
wet ice
儲存溫度
2-8°C
SMILES 字串
O=C1C=C(Oc2c1ccc3ccccc23)N4CCOCC4
InChI
1S/C17H15NO3/c19-15-11-16(18-7-9-20-10-8-18)21-17-13-4-2-1-3-12(13)5-6-14(15)17/h1-6,11H,7-10H2
InChI 密鑰
KKTZALUTXUZPSN-UHFFFAOYSA-N
應用
NU7026 已用于：
- 作为 DNA 依赖性蛋白激酶（DNA-PK）抑制剂，用于治疗结肠癌细胞
- 在激酶抑制剂实验中，用于处理在 20 h-人绒毛膜促性腺激素（hCG）后原核可见的受精卵
- 确定其对 dibenzo[def,p]chrysene 处理 HepG2 细胞的细胞毒性的影响
有效的，ATP 竞争。IC50 = 0.23 μM。对其他 PI3K 相关激酶的选择性（对于 PI3K，IC50 = 13 μM，对于 ATM 和 ATR 为 >100 μM）。
生化／生理作用
细胞可透过性 DNA-PK（DNA 依赖性蛋白激酶）小分子 benzochromenone 抑制剂。
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
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