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M6403

Sigma-Aldrich

(±)-3,4-亚甲二氧基甲基苯异丙胺 盐酸盐

别名:

(±)-MDMA 盐酸盐, DL-3,4-亚甲二氧基甲基苯异丙胺, DL-MDMA 盐酸盐, XTC 盐酸盐, 摇头丸

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About This Item

经验公式（希尔记法）:
C11H15NO2 · HCl
CAS号:
64057-70-1
分子量:
229.70
MDL號碼:
MFCD00079444
分類程式碼代碼:
12352116
PubChem物質ID:
24897006
NACRES:
NA.77

品質等級

200

藥物控制

USDEA Schedule I; Home Office Schedule 1; stupéfiant (France); kontrollierte Droge in Deutschland; regulated under CDSA - not available from Sigma-Aldrich Canada; psicótropo (Spain); Decreto Lei 15/93: Tabela IIA (Portugal)

技術

HPLC: suitable
gas chromatography (GC): suitable

溶解度

H2O: soluble

應用

forensics and toxicology
pharmaceutical (small molecule)
veterinary

SMILES 字串

Cl[H].CNC(C)Cc1ccc2OCOc2c1

InChI

1S/C11H15NO2.ClH/c1-8(12-2)5-9-3-4-10-11(6-9)14-7-13-10;/h3-4,6,8,12H,5,7H2,1-2H3;1H

InChI 密鑰

LUWHVONVCYWRMZ-UHFFFAOYSA-N

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生化／生理作用

迷幻剂；从轴突终末释放羟色胺和多巴胺；选择性血清素能神经毒素。

象形圖

Skull and crossbones
GHS06

訊號詞

Danger

危險聲明

H301,H336

防範說明

P301 + P310 + P330

危險分類

Acute Tox. 3 Oral - STOT SE 3

標靶器官

Central nervous system

儲存類別代碼

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

分析证书(COA)

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G A Ricaurte et al.
Neuropsychobiology, 42(1), 5-10 (2000-06-27)
The popular recreational drug, (+/-)3, 4-methylenedioxymethamphetamine (MDMA; 'Ecstasy') is a potent and selective brain serotonin (5-HT) neurotoxin in animals. MDMA-induced 5-HT neurotoxicity can be demonstrated using a variety of neurochemical, neuroanatomical and, more recently, functional measures of 5-HT neurons. Although
M I Colado et al.
British journal of pharmacology, 126(4), 911-924 (1999-04-08)
1. We investigated whether dopamine plays a role in the neurodegeneration of 5-hydroxytryptamine (5-HT) nerve endings occurring in Dark Agouti rat brain after 3,4-methylenedioxymethamphetamine (MDMA or 'ecstasy') administration. 2. Haloperidol (2 mg kg(-1) i.p.) injected 5 min prior and 55
A Lavelle et al.
British journal of pharmacology, 128(5), 975-980 (1999-11-11)
1. We have investigated the effects of methylenedioxymethamphetamine (MDMA, 'ecstasy') on peripheral noradrenergic neurotransmission in the rat. 2. In rat atrial slices pre-incubated with [3H]-noradrenaline and in the presence of desipramine (1 micronM) to prevent effects of MDMA on basal
M M Iravani et al.
Synapse (New York, N.Y.), 36(4), 275-285 (2000-05-20)
We examined the effects of pressure ejected 3, 4-methylenedioxymethamphetamine (MDMA) from a micropipette on direct chemically stimulated release, and on electrically stimulated serotonin (5-HT) or dopamine (DA) release in the caudate putamen (CPu), nucleus accumbens (NAc), substantia nigra pars reticulata
Mariana Angoa-Pérez et al.
Journal of neurochemistry, 125(1), 102-110 (2012-12-05)
Mephedrone (4-methylmethcathinone) is a β-ketoamphetamine stimulant drug of abuse with close structural and mechanistic similarities to methamphetamine. One of the most powerful actions associated with mephedrone is the ability to stimulate dopamine (DA) release and block its re-uptake through its
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