推荐产品
品質等級
化驗
≥98%
SMILES 字串
Cl[H].COc1ccc(CCN(C)CCCC(C#N)(C(C)C)c2cc(OC)c(OC)c(OC)c2)cc1OC
InChI
1S/C28H40N2O5.ClH/c1-20(2)28(19-29,22-17-25(33-6)27(35-8)26(18-22)34-7)13-9-14-30(3)15-12-21-10-11-23(31-4)24(16-21)32-5;/h10-11,16-18,20H,9,12-15H2,1-8H3;1H
InChI 密鑰
OKCRIUNHEQSXFD-UHFFFAOYSA-N
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一般說明
甲氧维拉帕米是一种钙调素拮抗剂。通过调节钙信号控制鞭毛糖蛋白再分布。甲氧维拉帕米影响细胞内钙水平的影响,并影响精子获能功能。
應用
(±)-甲氧基维拉帕米盐酸盐已被用于:
- 在 曼氏血吸虫 寄生虫
- 中作为钙通道拮抗剂在培养的巨噬细胞中作为钙条目阻滞剂
- 在 L 型电压门控 Ca 2 + 通道抑制
生化/生理作用
阻断 L 型 Ca2+ 通道
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
其他客户在看
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To quantitatively assess the effect of lowering external Ca(2+) ([Ca(2+)](o)) on both endothelium-dependent and -independent relaxations in rabbit aorta. Isometric contractions and relaxations of isolated aortae were recorded. When assessing the effect of reduced [Ca(2+)](o) on relaxations, the normal [Ca(2+)](o)
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Embryonic stem (ES) cells are provided as a powerful tool for developmental biology and have been shown to respond to insulin. However, little is known about the effect of insulin on [Ca2+]i regulation in the ES cells, although many cellular
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American journal of physiology. Cell physiology, 286(6), C1353-C1357 (2004-01-30)
At the end of the force transient elicited by a fast stretch applied to an activated frog muscle fiber, the force settles to a steady level exceeding the isometric level preceding the stretch. We showed previously that this excess of
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Ab initio Hartree-Fock calculations have been performed at the 6-31G level to study the pharmacophoric features of verapamil. Both the unprotonated and the protonated forms of verapamil have been studied. The study predicts that the drug enters the body in
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Molecular nutrition & food research, 51(4), 468-472 (2007-03-16)
Melanoidins obtained from L-arginine and D-glucose (MW > 3500 Da) were tested for their ability to influence the contractility of gastric smooth muscles. A study within the range 0.1-10 mg/mL revealed that at low concentrations, the melanoidins provoked concentration-dependent contraction
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