所有图片(2)
About This Item
经验公式（希尔记法）:
C16H18N2O6
CAS号:
分子量:
334.32
Beilstein:
1555271
MDL號碼:
分類程式碼代碼:
12352103
PubChem物質ID:
NACRES:
NC.07
化驗
≥98%
形狀
powder
反應適用性
reagent type: linker
mp
180-182 °C (lit.)
溶解度
chloroform: 50 mg/mL
DMF: soluble
官能基
NHS ester
運輸包裝
wet ice
儲存溫度
−20°C
SMILES 字串
O=C(ON1C(CCC1=O)=O)C2CCC(CN3C(C=CC3=O)=O)CC2
InChI
1S/C16H18N2O6/c19-12-5-6-13(20)17(12)9-10-1-3-11(4-2-10)16(23)24-18-14(21)7-8-15(18)22/h5-6,10-11H,1-4,7-9H2
InChI 密鑰
JJAHTWIKCUJRDK-UHFFFAOYSA-N
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一般說明
4-（N-马来酰亚胺基甲基）环己烷羧酸 N-羟基琥珀酰亚胺酯（SMCC）是一种异双功能交联剂，其包含一个具有胺和巯基反应性的延长间隔基。它通常首先通过酰胺键（pH7.5（6.5-8.5）缓冲）与含有伯胺的分子进行偶联。第二次偶联通过硫醚键（pH6.8（6.5-7.0）缓冲）与含有游离巯基的分子进行特异性偶联。SMCC包含九个原子连接子。与芳族间隔基相比，延伸的脂族间隔基可在偶联之前稳定马来酰亚胺。
應用
4-（N-马来酰亚胺基甲基）环己烷羧酸 N-羟基琥珀酰亚胺酯（SMCC）可用于制备酶免疫结合物和半抗原载体分子结合物。它已用于将肽序列与氨基进行偶联。
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
dust mask type N95 (US), Eyeshields, Gloves
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