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Merck

M3529

Sigma-Aldrich

L-蛋氨酸对硝基苯胺

≥98% (TLC), suitable for ligand binding assays

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About This Item

经验公式(希尔记法):
C11H15N3O3S
CAS号:
分子量:
269.32
MDL號碼:
分類程式碼代碼:
12352209
PubChem物質ID:
NACRES:
NA.26

product name

L-蛋氨酸对硝基苯胺,

化驗

≥98% (TLC)

形狀

powder

技術

ligand binding assay: suitable

顏色

white to faint yellow

儲存溫度

−20°C

SMILES 字串

CSCC[C@H](N)C(=O)Nc1ccc(cc1)[N+]([O-])=O

InChI

1S/C11H15N3O3S/c1-18-7-6-10(12)11(15)13-8-2-4-9(5-3-8)14(16)17/h2-5,10H,6-7,12H2,1H3,(H,13,15)/t10-/m0/s1

InChI 密鑰

PLBWRAWSHVJPTL-JTQLQIEISA-N

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生化/生理作用

L-蛋氨酸对硝基苯胺是一种hMetAP2底物。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Sanghamitra Mitra et al.
Analytical biochemistry, 357(1), 43-49 (2006-07-18)
A direct and convenient spectrophotometric assay has been developed for methionine aminopeptidases (MetAPs). The method employs the hydrolysis of a substrate that is a methionyl analogue of p-nitroaniline (L-Met-p-NA), which releases the chromogenic product p-nitroaniline. This chromogenic product can be
G Yang et al.
Biochemistry, 40(35), 10645-10654 (2001-08-29)
The steady-state kinetics of a full-length and truncated form of the type 2 human methionine aminopeptidase (hMetAP2) were analyzed by continuous monitoring of the amide bond cleavage of various peptide substrates and methionyl analogues of 7-amido-4-methylcoumarin (AMC) and p-nitroaniline (pNA)
R A Cowman et al.
Journal of dental research, 70(12), 1508-1515 (1991-12-01)
Intact cells of Streptococcus sanguis ATCC 10556 possessed arylaminopeptidases exhibiting activity toward the nitroanilide (NA) derivatives of leucine, alanine, methionine, arginine, or lysine. Weak hydrolytic activity was observed in assays with the NA derivatives of valine, proline, glycine, or glutamic

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