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Merck

M1568

Sigma-Aldrich

甘露糖三氟磺酸酯

For PET imaging, ≥98% (TLC)

别名:

β-D-甘露吡喃糖1,3,4,6-四- O -乙酸盐 2- O -三氟甲磺酸酯, 1,3,4,6-四-O-乙酰基-2-O-三氟甲磺酰-β-D-吡喃甘露糖, TATM, 甘露糖三氟甲磺酸酯

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About This Item

经验公式(希尔记法):
C15H19F3O12S
CAS号:
分子量:
480.36
Beilstein:
4341413
MDL號碼:
分類程式碼代碼:
41116107
PubChem物質ID:
NACRES:
NA.12

品質等級

化驗

≥98% (TLC)

技術

PET imaging: suitable

運輸包裝

dry ice

儲存溫度

−20°C

SMILES 字串

CC(=O)OC[C@H]1O[C@@H](OC(C)=O)[C@@H](OS(=O)(=O)C(F)(F)F)[C@@H](OC(C)=O)[C@@H]1OC(C)=O

InChI

1S/C15H19F3O12S/c1-6(19)25-5-10-11(26-7(2)20)12(27-8(3)21)13(14(29-10)28-9(4)22)30-31(23,24)15(16,17)18/h10-14H,5H2,1-4H3/t10-,11-,12+,13+,14-/m1/s1

InChI 密鑰

OIBDVHSTOUGZTJ-PEBLQZBPSA-N

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相关类别

一般說明

Mannose triflate is a glucose analogue.

應用

Mannose triflate is a well-known precursor for 18F-FDG synthesis for PET applications. The binding of 18F to the mannose triflate has been carried out via SN2 nucleophilic substitution reaction. It is used in computational tomography, an imaging technique in early detection of cancer.

其他說明

This formulation of mannose triflate has reduced trace impurities that are known to cause lower synthetic yields.

應用

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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分析证书(COA)

Lot/Batch Number

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Ren Iwata et al.
Journal of labelled compounds & radiopharmaceuticals, 61(7), 540-549 (2018-03-10)
High specific activity is often a significant requirement for radiopharmaceuticals. To achieve that with fluorine-18 (18 F)-labeled probes, it is mandatory to start from no-carrier-added fluoride and to reduce to a minimum the amount of precursor in order to decrease
Gulcan Unak et al.
Colloids and surfaces. B, Biointerfaces, 90, 217-226 (2011-11-11)
A new architecture has been designed by the conjugation of [(18)F]2-fluoro-2-deoxy-D-glucose ((18)F-FDG), gold nanoparticles (AuNPs), and anti-metadherin (Anti-MTDH) antibody which is specific to the metadherin (MTDH) over-expressed on the surface of breast cancer cells. Mannose triflate molecule is used as
Shane B Claggett et al.
EJNMMI research, 3(1), 53-53 (2013-07-17)
Many automated radiosynthesizers for producing positron emission tomography (PET) probes provide a means for the operator to create custom synthesis programs. The programming interfaces are typically designed with the engineer rather than the radiochemist in mind, requiring lengthy programs to
Padgett, H., et al.
Applied Radiation and Isotopes, 40, 433-433 (1989)
Martin Thunemann et al.
Nature communications, 8(1), 444-444 (2017-09-07)
Many pathophysiological processes are associated with proliferation, migration or death of distinct cell populations. Monitoring specific cell types and their progeny in a non-invasive, longitudinal and quantitative manner is still challenging. Here we show a novel cell-tracking system that combines

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