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L7134

Sigma-Aldrich

人促黄体激素释放激素 乙酸盐

≥98% (HPLC), powder

别名:

Gonadoliberin, Gonadotropin releasing hormone, LH-RH

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About This Item

经验公式（希尔记法）:
C55H75N17O13
CAS号:
71447-49-9
分子量:
1182.29
MDL號碼:
MFCD00133489
分類程式碼代碼:
51111800
PubChem物質ID:
329817648
NACRES:
NA.32

品質等級

200

化驗

≥98% (HPLC)

形狀

powder

分子量

Mr 1182.33

UniProt登錄號

P01148

儲存溫度

−20°C

SMILES 字串

CC(O)=O.CC(O)=O.CC(C)C[C@H](NC(=O)CNC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc4c[nH]cn4)NC(=O)[C@@H]5CCC(=O)N5)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N6CCC[C@H]6C(=O)NCC(N)=O

InChI

1S/C55H75N17O13.2C2H4O2/c1-29(2)19-38(49(80)67-37(9-5-17-60-55(57)58)54(85)72-18-6-10-43(72)53(84)62-25-44(56)75)66-46(77)26-63-47(78)39(20-30-11-13-33(74)14-12-30)68-52(83)42(27-73)71-50(81)40(21-31-23-61-35-8-4-3-7-34(31)35)69-51(82)41(22-32-24-59-28-64-32)70-48(79)36-15-16-45(76)65-36;2*1-2(3)4/h3-4,7-8,11-14,23-24,28-29,36-43,61,73-74H,5-6,9-10,15-22,25-27H2,1-2H3,(H2,56,75)(H,59,64)(H,62,84)(H,63,78)(H,65,76)(H,66,77)(H,67,80)(H,68,83)(H,69,82)(H,70,79)(H,71,81)(H4,57,58,60);2*1H3,(H,3,4)/t36-,37-,38-,39-,40-,41-,42-,43-;;/m0../s1

InChI 密鑰

QOVPLTBEZAJSHY-VIRDRFNDSA-N

基因資訊

human ... GNRH1(2796)

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Amino Acid Sequence

Glp-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2

應用

Luteinizing hormone releasing hormone human acetate salt has been used:
  • for synchronization of the ovulations
  • for pre-absorption of the anti-GnRH antibody in staining procedures
  • to study pituitary sensitivity to GnRH in presence of endocrine disrupting compound

生化／生理作用

Hypothalamic peptide that stimulates release of gonadotrophins from anterior pituitary, thus regulating reproductive functions.

包裝

Bottomless glass bottle. Contents are inside inserted fused cone.

成分

pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2

其他說明

free peptide
Lyophilized from 0.5% acetic acid

象形圖

Health hazard
GHS08

訊號詞

Danger

危險聲明

H360

防範說明

P201 - P308 + P313

危險分類

Repr. 1B

儲存類別代碼

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges

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Histological characterization of gonadotropin-releasing hormone
(GnRH) in the hypothalamus of the South American plains
vizcacha (Lagostomus maximus)
Veronica, et.la
Journal of Molecular Histology (2011)
Developmental Programming: Impact of Prenatal Exposure to Bisphenol-A and Methoxychlor on Steroid Feedbacks in Sheep
Bachir Abi Salloum
Toxicology and Applied Pharmacology (2013)
Nicholas A Levis et al.
Ecology and evolution, 5(7), 1405-1411 (2015-04-22)
Phenotypic plasticity is commonplace, and plasticity theory predicts that organisms should often evolve mechanisms to detect and respond to environmental cues that accurately predict future environmental conditions. Here, we test this prediction in tadpoles of spadefoot toads, Spea multiplicata. These
First birth of an animal from an extinct subspecies
(Capra pyrenaica pyrenaica) by cloning
J. Folch
Theriogenology (2009)
ERa and GnRH co-localize in the hypothalamic neurons of the South American plains vizcacha, Lagostomus maximus (Rodentia, Caviomorpha)
Pablo Ignacio
Journal of Molecular Histology (2017)
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