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Merck

L6004

Sigma-Aldrich

林可霉素 盐酸盐

≥90% (TLC)

别名:

Methyl 6,8-dideoxy-6-(1-methyl-4-propyl-2-pyrrolidinecarboxamido)-1-thio-D-erythro-α-D-galactooctopyranoside 盐酸盐, 林可霉素 盐酸盐

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About This Item

经验公式(希尔记法):
C18H34N2O6S · HCl
CAS号:
分子量:
443.00
Beilstein:
4171650
EC號碼:
MDL號碼:
分類程式碼代碼:
51284507
PubChem物質ID:
NACRES:
NA.85

化驗

≥90% (TLC)

效力

800-900 units per mg

顏色

white to faint yellow

溶解度

H2O: soluble 50 mg/mL

抗生素活性譜

Gram-positive bacteria

作用方式

protein synthesis | interferes

儲存溫度

2-8°C

SMILES 字串

Cl.CCC[C@@H]1C[C@H](N(C)C1)C(=O)N[C@H]([C@@H](C)O)[C@H]2O[C@H](SC)[C@H](O)[C@@H](O)[C@H]2O

InChI

1S/C18H34N2O6S.ClH/c1-5-6-10-7-11(20(3)8-10)17(25)19-12(9(2)21)16-14(23)13(22)15(24)18(26-16)27-4;/h9-16,18,21-24H,5-8H2,1-4H3,(H,19,25);1H/t9-,10-,11+,12-,13+,14-,15-,16-,18-;/m1./s1

InChI 密鑰

POUMFISTNHIPTI-BOMBIWCESA-N

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一般說明

化学结构:大环内酯

應用

盐酸林可霉素是一种抗生素,用于研究蛋白质合成抑制、细菌抗生素耐药性以及蛋白质和表面活性剂的结合 它是由 链霉菌 var. Lincolnensis 产生。

生化/生理作用

作用方式:林可霉素可通过在23S rRNA的肽基转移酶环区域内形成交联来抑制细菌蛋白质的合成。†

抗菌谱:盐酸林可霉素对革兰氏阳性菌有效。

準備報告

该产品在水中的溶解度为50 mg/mL,产生澄清无色的溶液。

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Journal of biochemistry, 148(1), 71-84 (2010-04-02)
The thermodynamics of interaction of neomycin and lincomycin with bovine serum albumin (BSA) and human serum albumin (HSA) has been studied using isothermal titration calorimetry (ITC), in combination with UV-visible, steady state and time resolved fluorescence spectroscopic measurements. Neomycin is
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A new type of multi-color PAM chlorophyll fluorometer (Schreiber et al. 2012) was applied for measurements of photodamage to photosystem II (PS II) in optically thin suspensions of Chlorella (200 μg Chl l(-1)) in the presence of 1 mM lincomycin.
Isaac M Hagenbuch et al.
Water research, 46(16), 5028-5036 (2012-07-24)
The role that antibiotics and other "emerging contaminants" play in shaping environmental microbial communities is of growing interest. The use of the prokaryotic metabolic inhibitors tylosin (T), lincomycin (L), and ciprofloxacin (C) in livestock and humans is both global and

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