所有图片(1)
About This Item
经验公式(希尔记法):
C20H32O5
CAS号:
分子量:
352.47
EC號碼:
MDL號碼:
分類程式碼代碼:
12352211
PubChem物質ID:
NACRES:
NA.77
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形狀
ethanol solution
品質等級
運輸包裝
dry ice
儲存溫度
−20°C
SMILES 字串
CCCCC[C@H](O)\C=C\C=C/C=C/C=C/[C@@H](O)[C@@H](O)CCCC(O)=O
InChI
1S/C20H32O5/c1-2-3-8-12-17(21)13-9-6-4-5-7-10-14-18(22)19(23)15-11-16-20(24)25/h4-7,9-10,13-14,17-19,21-23H,2-3,8,11-12,15-16H2,1H3,(H,24,25)/b6-4-,7-5+,13-9+,14-10+/t17-,18+,19-/m0/s1
InChI 密鑰
IXAQOQZEOGMIQS-SSQFXEBMSA-N
生化/生理作用
脂蛋白A4(LXA4)由花生四烯酸合成,是一种内源性脂氧合酶衍生的类花生酸介体。它是一种有效的人蛋白激酶C激活剂。它抑制自然杀伤细胞的细胞毒性。LXA4调节免疫系统和炎症。在大脑中,它调节神经元信号传导和慢波睡眠。LXA4与大麻素受体结合。LXA4在子宫内膜和生殖功能的维持中起关键作用。LXA4的消耗有助于囊性纤维化(CF)的病理生理。
包裝
氩气包装。
訊號詞
Danger
危險聲明
危險分類
Eye Irrit. 2 - Flam. Liq. 2
儲存類別代碼
3 - Flammable liquids
水污染物質分類(WGK)
WGK 2
閃點(°F)
55.4 °F
閃點(°C)
13 °C
個人防護裝備
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
Physiological impact of abnormal lipoxin A4 production on cystic fibrosis airway epithelium and therapeutic potential.
Higgins G, et al.
BioMed Research International, 2015(3), 439-439 (2015)
Anti-inflammatory lipoxin A4 is an endogenous allosteric enhancer of CB1 cannabinoid receptor.
Pamplona FA, et al.
Proceedings of the National Academy of Sciences of the USA, 109(51), 21134-21139 (2012)
Stephanie G Dakin et al.
Scientific reports, 7(1), 11009-11009 (2017-09-10)
The mechanisms underpinning the failure of inflammation to resolve in diseased musculoskeletal soft tissues are unknown. Herein, we studied bioactive lipid mediator (LM) profiles of tendon-derived stromal cells isolated from healthy donors and patients with chronic tendinopathy. Interleukin(IL)-1β treatment markedly
The role of lipoxin A 4 in endometrial biology and endometriosis.
Canny GO and Lessey BA
Mucosal Immunology, 6(3), 439-439 (2013)
The lipoxin receptor ALX: potent ligand-specific and stereoselective actions in vivo.
Chiang N, et al.
Pharmacological Reviews, 58(3), 463-487 (2006)
商品
The potential for the prevention and treatment of cardiovascular disease through increased dietary intake of omega-3 (w-3) fish oils is not a recent scientific discovery.
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